NOL7 and CD83

		NOL7	CD83
Description		nucleolar protein 7	CD83 molecule
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GO Annotations	Cellular Component	Nucleus Chromosome Nucleolus Mitochondrion Small-subunit Processome	Plasma Membrane External Side Of Plasma Membrane Membrane
	Molecular Function	RNA Binding Protein Binding	Protein Binding
	Biological Process	Maturation Of SSU-rRNA Ribosome Biogenesis Ribosomal Small Subunit Biogenesis	Immune System Process Defense Response Humoral Immune Response Signal Transduction Negative Regulation Of Interleukin-4 Production Positive Regulation Of Interleukin-10 Production Positive Regulation Of Interleukin-2 Production CD4-positive, Alpha-beta T Cell Differentiation Positive Regulation Of CD4-positive, Alpha-beta T Cell Differentiation
Pathways
Drugs
Diseases
GWAS			Breast cancer and/or colorectal cancer ( 29698419) California verbal learning test score ( 31596458) Chronotype ( 30696823) Obesity-related traits ( 23251661) Response to tofacitinib treatment (herpes zoster) ( 33455090) Response to tofacitinib treatment (herpes zoster)(time to event) ( 33455090) Response to tofacitinib treatment in psoriasis (herpes zoster) ( 33455090) Response to tofacitinib treatment in psoriasis (herpes zoster)(time to event) ( 33455090) Rheumatoid arthritis ( 22446963 24390342 30423114)
Interacting Genes		4 interacting genes: APP C8orf33 CALM1 CCNDBP1	2 interacting genes: EIF4E FATE1
Entrez ID		51406	9308
HPRD ID		17641	05170
Ensembl ID		ENSG00000225921	ENSG00000112149
Uniprot IDs		Q9UMY1	A0A087WX61 Q01151
PDB IDs		7MQ8 7MQ9 7MQA	5MIX 5MJ0 5MJ1 5MJ2
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Regulation Of Calcium Ion Transmembrane Transport Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Regulation Of Synaptic Plasticity Calcium-mediated Signaling Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Positive Regulation Of Synaptic Transmission Regulation Of Calcium-mediated Signaling Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Calcium Ion Export Across Plasma Membrane Adenylate Cyclase Activator Activity Negative Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Regulation Of Calcium Ion Transport Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Transporter Inhibitor Activity Regulation Of Calcium Ion Export Across Plasma Membrane Axon Choice Point Recognition Mitochondrion-endoplasmic Reticulum Membrane Tethering Positive Regulation Of Sequestering Of Calcium Ion Autophagosome Membrane Docking Negative Regulation Of Interleukin-4 Production	Eukaryotic Initiation Factor 4G Binding GMP Reductase Activity GMP Reductase Complex Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Positive Regulation Of Estradiol Secretion 3'-phosphoadenosine 5'-phosphosulfate Biosynthetic Process Sulfate Assimilation Sulfate Adenylyltransferase (ATP) Activity Adenylylsulfate Kinase Activity Regulation Of Translation At Postsynapse, Modulating Synaptic Transmission Regulation Of Estradiol Secretion
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