IFT52 and SPINT3

		IFT52	SPINT3
Description		intraflagellar transport 52	serine peptidase inhibitor, Kunitz type 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Centrosome Centriole Cilium Intraciliary Transport Particle B Motile Cilium Photoreceptor Connecting Cilium Ciliary Basal Body Cell Projection Dendrite Terminus Ciliary Tip Ciliary Base Photoreceptor Cell Cilium	Extracellular Region
	Molecular Function	Protein Binding	Serine-type Endopeptidase Inhibitor Activity Peptidase Inhibitor Activity
	Biological Process	Neural Tube Formation Heart Looping Smoothened Signaling Pathway Determination Of Left/right Symmetry Dorsal/ventral Pattern Formation Negative Regulation Of Keratinocyte Proliferation Cell Projection Organization Intraciliary Anterograde Transport Intraciliary Transport Embryonic Digit Morphogenesis Keratinocyte Proliferation Cilium Assembly Regulation Of Protein Processing Non-motile Cilium Assembly
Pathways		Hedgehog 'off' state Intraflagellar transport Intraflagellar transport
Drugs
Diseases
GWAS		Mean reticulocyte volume ( 32888494)	Blood protein levels ( 30072576) Brain structure ( 20171287)
Interacting Genes
Entrez ID		51098	10816
HPRD ID		12789	19468
Ensembl ID		ENSG00000101052	ENSG00000101446
Uniprot IDs		Q9Y366	P49223
PDB IDs
Enriched GO Terms of Interacting Partners?		Serine-type Endopeptidase Inhibitor Activity Protein Targeting To Mitochondrion Establishment Of Protein Localization To Mitochondrion Heat Shock Protein Binding Peptidase Inhibitor Activity	Photoreceptor Cell Cilium Neural Tube Formation Dendrite Terminus Epithelial Tube Formation Non-motile Cilium Assembly Embryonic Epithelial Tube Formation Embryonic Digit Morphogenesis Ciliary Tip Regulation Of Keratinocyte Proliferation Dorsal/ventral Pattern Formation Negative Regulation Of Keratinocyte Proliferation Regulation Of Protein Processing Intraciliary Transport Particle B Photoreceptor Connecting Cilium Keratinocyte Proliferation Heart Looping Embryonic Heart Tube Morphogenesis Intraciliary Transport Regulation Of Protein Maturation Ciliary Base Intraciliary Anterograde Transport Smoothened Signaling Pathway Determination Of Bilateral Symmetry Determination Of Left/right Symmetry Epithelial Tube Morphogenesis Tube Formation Negative Regulation Of Epithelial Cell Proliferation Centriole Transport Along Microtubule Epithelial Cell Proliferation Cytoskeleton-dependent Intracellular Transport Microtubule-based Transport Motile Cilium Cilium Assembly Regionalization Tube Morphogenesis Cilium Organization Ciliary Basal Body Morphogenesis Of An Epithelium Plasma Membrane Bounded Cell Projection Assembly Regulation Of Epithelial Cell Proliferation Cell Projection Assembly Regulation Of Proteolysis Pattern Specification Process Tissue Morphogenesis Microtubule-based Movement Embryonic Morphogenesis
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