NPTX1 and ZNF92

		NPTX1	ZNF92
Description		neuronal pentraxin 1	zinc finger protein 92
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Transport Vesicle Cytoplasmic Vesicle Synaptic Cleft Glutamatergic Synapse	Nucleus
	Molecular Function	Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Mitochondrial Transport Chemical Synaptic Transmission Central Nervous System Development Cellular Response To Potassium Ion Mitochondrial Fragmentation Involved In Apoptotic Process Axonogenesis Involved In Innervation Cellular Response To Glucose Stimulus Postsynaptic Density Assembly Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Blood protein levels ( 30072576)
Interacting Genes		3 interacting genes: ADRB2 NPTXR RCN2	4 interacting genes: APP CREB1 MEOX2 STAT6
Entrez ID		4884	168374
HPRD ID		03843	04919
Ensembl ID		ENSG00000171246	ENSG00000146757
Uniprot IDs		Q15818	C9IZS8 Q03936 V9HVY7
PDB IDs		6YPE
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Excitatory Postsynaptic Potential Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Modulation Of Excitatory Postsynaptic Potential Positive Regulation Of Mini Excitatory Postsynaptic Potential Positive Regulation Of Spontaneous Neurotransmitter Secretion Negative Regulation Of Macropinocytosis Negative Regulation Of Synaptic Vesicle Recycling	Cell Activation Involved In Immune Response Positive Regulation Of Long-term Synaptic Potentiation Axonogenesis Cellular Response To Metal Ion Isotype Switching Somatic Recombination Of Immunoglobulin Genes Involved In Immune Response Somatic Diversification Of Immunoglobulins Involved In Immune Response Cell Projection Morphogenesis Response To Nerve Growth Factor Neuron Projection Morphogenesis Regulation Of Long-term Synaptic Potentiation Cellular Response To Nerve Growth Factor Stimulus Somatic Recombination Of Immunoglobulin Gene Segments Somatic Cell DNA Recombination Somatic Diversification Of Immunoglobulins Response To Metal Ion Chemotaxis Regulation Of T Cell Migration Transcription Coactivator Binding Visual Learning Positive Regulation Of Immune System Process Locomotion Visual Behavior Regulation Of Multicellular Organism Growth Immune Effector Process B Cell Activation Involved In Immune Response Regulation Of Lymphocyte Migration Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Isotype Switching To IgA Isotypes DN3 Thymocyte Differentiation Chemotaxis To Arachidonate DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of Transcription By RNA Polymerase II Sequence-specific DNA Binding Associative Learning Positive Regulation Of Mononuclear Cell Migration Positive Regulation Of Leukocyte Chemotaxis Acetylcholine Receptor Activator Activity Anatomical Structure Morphogenesis Lipoprotein Particle Developmental Process Leukocyte Activation Positive Regulation Of Protein Import Positive Regulation Of Flagellated Sperm Motility Involved In Capacitation Positive Regulation Of Cardiac Muscle Tissue Development Positive Regulation Of Transforming Growth Factor Beta3 Production
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