SULT1C3 and GCC2

		SULT1C3	GCC2
Description		sulfotransferase family 1C member 3	GRIP and coiled-coil domain containing 2
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GO Annotations	Cellular Component	Cytoplasm	Nucleoplasm Cytoplasm Golgi Apparatus Trans-Golgi Network Cytosol Membrane
	Molecular Function	Alcohol Sulfotransferase Activity Aryl Sulfotransferase Activity Protein Binding Sulfotransferase Activity Transferase Activity Bile-salt Sulfotransferase Activity 3'-phosphoadenosine 5'-phosphosulfate Binding	Protein Binding Small GTPase Binding Identical Protein Binding
	Biological Process	Lipid Metabolic Process Sulfur Compound Metabolic Process Xenobiotic Metabolic Process Cholesterol Metabolic Process 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Sulfation	Protein Targeting To Lysosome Protein Transport Microtubule Organizing Center Organization Protein Localization To Golgi Apparatus Microtubule Anchoring Late Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Golgi To Plasma Membrane Protein Transport Regulation Of Protein Exit From Endoplasmic Reticulum Recycling Endosome To Golgi Transport Golgi Ribbon Formation
Pathways			Retrograde transport at the Trans-Golgi-Network Signaling by ALK fusions and activated point mutants
Drugs
Diseases
GWAS		Aluminium levels ( 26025379) Blood pressure ( 24954895) Diastolic blood pressure ( 27618448) Eyebrow thickness ( 26926045) Systolic blood pressure ( 27618448)	Excessive hairiness ( 29895819) Eyebrow thickness ( 26926045) Liver enzyme levels (alkaline phosphatase) ( 33972514) Low density lipoprotein cholesterol levels ( 32154731) Mean platelet volume ( 27863252) Platelet distribution width ( 32888494)
Interacting Genes		1 interacting genes: SULT2B1	3 interacting genes: ARL1 SPOP SRPK2
Entrez ID		442038	9648
HPRD ID		18131	11001
Ensembl ID		ENSG00000196228	ENSG00000135968
Uniprot IDs		Q6IMI6	A0A8I5QJB7 B3KR21 Q8IWJ2
PDB IDs		2H8K 2REO	3BBP
Enriched GO Terms of Interacting Partners?		Alcohol Sulfotransferase Activity Cholesterol Sulfotransferase Activity Steroid Sulfotransferase Activity Steroid Hormone Binding Recycling Endosome To Golgi Transport Late Endosome To Golgi Transport 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Golgi Ribbon Formation Sulfation Small Molecule Binding Microtubule Anchoring Regulation Of Protein Exit From Endoplasmic Reticulum Positive Regulation Of Epidermal Cell Differentiation Protein Localization To Golgi Apparatus Protein Targeting To Lysosome Positive Regulation Of Epidermis Development Golgi To Plasma Membrane Protein Transport Sulfotransferase Activity Cholesterol Binding Protein Targeting To Vacuole Regulation Of Epidermis Development Positive Regulation Of Epithelial Cell Differentiation Regulation Of Epidermal Cell Differentiation Protein Localization To Lysosome Establishment Of Protein Localization To Vacuole Establishment Of Protein Localization To Plasma Membrane Golgi To Plasma Membrane Transport Microtubule Organizing Center Organization Protein Localization To Vacuole Retrograde Transport, Endosome To Golgi Post-Golgi Vesicle-mediated Transport Cholesterol Metabolic Process Sterol Metabolic Process Lysosomal Transport Golgi Organization
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