KIF7 and ZNF710

		KIF7	ZNF710
Description		kinesin family member 7	zinc finger protein 710
Image			No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Cytoplasm Cytosol Cytoskeleton Kinesin Complex Microtubule Cilium Ciliary Basal Body Cell Projection Ciliary Tip	Nucleus
	Molecular Function	Nucleotide Binding Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP Hydrolysis Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Microtubule-based Movement Negative Regulation Of Smoothened Signaling Pathway Positive Regulation Of Smoothened Signaling Pathway	Regulation Of Transcription By RNA Polymerase II
Pathways		Hedgehog 'off' state Hedgehog 'on' state	Generic Transcription Pathway
Drugs
Diseases
GWAS		Cobalt levels ( 26025379)	Body size at age 10 ( 32376654) Lymphocyte count ( 32888494) Lymphocyte percentage of white cells ( 32888494) Mean platelet volume ( 32888494) Platelet count ( 32888494) Platelet distribution width ( 32888494)
Interacting Genes		1 interacting genes: FXR2	2 interacting genes: DYNLL1 POGZ
Entrez ID		374654	374655
HPRD ID		14187	13329
Ensembl ID		ENSG00000166813	ENSG00000140548
Uniprot IDs		A0A8Q3SIQ8 Q2M1P5	Q8N1W2
PDB IDs		2XT3 4A14 6MLQ 6MLR 7RX0
Enriched GO Terms of Interacting Partners?		Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase Activity GDP-D-glucose Phosphorylase Activity Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Positive Regulation Of Long-term Neuronal Synaptic Plasticity	Ciliary Tip Deoxyribonuclease Inhibitor Activity Negative Regulation Of DNA Strand Resection Involved In Replication Fork Processing Regulation Of DNA Strand Resection Involved In Replication Fork Processing Nitric-oxide Synthase Inhibitor Activity Ciliary Basal Body Microtubule Nitric-oxide Synthase Regulator Activity Microtubule-based Movement Negative Regulation Of Nitric Oxide Biosynthetic Process Intraciliary Retrograde Transport DNA Strand Resection Involved In Replication Fork Processing Negative Regulation Of DNA-templated DNA Replication Kinetochore Assembly Cilium Mitotic Sister Chromatid Cohesion Kinetochore Organization Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Cytoplasmic Dynein Complex Negative Regulation Of DNA Replication COP9 Signalosome DNA Metabolic Process Dynein Intermediate Chain Binding DNA Damage Response Dynein Complex Chromosome Microtubule Associated Complex Organelle Assembly Microtubule-based Process Negative Regulation Of Smoothened Signaling Pathway Positive Regulation Of Smoothened Signaling Pathway Substantia Nigra Development Motile Cilium Assembly Sister Chromatid Cohesion Kinesin Complex Intraciliary Transport
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