RSPH4A and AFG1L

		RSPH4A	AFG1L
Description		radial spoke head component 4A	AFG1 like ATPase
Image			No pdb structure
GO Annotations	Cellular Component	Radial Spoke Radial Spoke Head Extracellular Region Cytoplasm Cytoskeleton Cilium Axoneme Motile Cilium Cell Projection 9+2 Motile Cilium Radial Spoke Head 1 Radial Spoke Head 2 Radial Spoke Head 3	Cytoplasm Mitochondrion Membrane Mitochondrial Membrane
	Molecular Function		Nucleotide Binding Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity
	Biological Process	Cilium Movement Epithelial Cilium Movement Involved In Extracellular Fluid Movement Cell Projection Organization Axoneme Assembly Establishment Of Localization In Cell Cilium Assembly Cilium Movement Involved In Cell Motility Radial Spoke Assembly Maintenance Of Ciliary Planar Beating Movement Pattern	Mitochondrion Organization Mitochondrial Protein Catabolic Process Mitochondrial Protein Quality Control
Pathways
Drugs
Diseases		Primary ciliary dyskinesia, including: Primary ciliary dyskinesia; Kartagener syndrome
GWAS
Interacting Genes			2 interacting genes: BANP CIDEB
Entrez ID		345895	246269
HPRD ID		18005	11223
Ensembl ID		ENSG00000111834	ENSG00000135537
Uniprot IDs		B3KTA9 Q5TD94	Q8WV93
PDB IDs		8J07
Enriched GO Terms of Interacting Partners?		ATP Export ATP Transport Purine Nucleotide Transport Adenine Nucleotide Transport Monoatomic Cation Channel Activity Nucleotide Transport Carbohydrate Derivative Transport [heparan Sulfate]-glucosamine 3-sulfotransferase Activity Protein Sulfation Mitochondrial Protein Quality Control Organophosphate Ester Transport Voltage-gated Channel Activity Nucleobase-containing Compound Transport 3'-phosphoadenosine 5'-phosphosulfate Binding Mitochondrial Protein Catabolic Process Regulation Of Natural Killer Cell Cytokine Production Organic Anion Transport Sulfation Regulation Of Viral Entry Into Host Cell Heparan Sulfate Proteoglycan Biosynthetic Process	Radial Spoke Head 2 Maintenance Of Ciliary Planar Beating Movement Pattern Radial Spoke Head 1 Radial Spoke Assembly Radial Spoke Head 3 Lipid Droplet Fusion Radial Spoke Head COPI-coated Vesicle Lipid Transfer Activity Very-low-density Lipoprotein Particle Assembly Radial Spoke COPII Vesicle Coat COPII-coated Vesicle Cargo Loading Execution Phase Of Apoptosis Phosphatidic Acid Binding Protein-lipid Complex Assembly Plasma Lipoprotein Particle Assembly Lipid Storage Intermembrane Lipid Transfer Vesicle Cargo Loading 9+2 Motile Cilium Regulation Of Cilium Movement Lipid Droplet Organization Regulation Of Triglyceride Metabolic Process Axoneme Assembly Extracellular Transport Epithelial Cilium Movement Involved In Extracellular Fluid Movement Regulation Of Microtubule-based Movement Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
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