RSPH4A and HS3ST5

		RSPH4A	HS3ST5
Description		radial spoke head component 4A	heparan sulfate-glucosamine 3-sulfotransferase 5
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GO Annotations	Cellular Component	Radial Spoke Radial Spoke Head Extracellular Region Cytoplasm Cytoskeleton Cilium Axoneme Motile Cilium Cell Projection 9+2 Motile Cilium Radial Spoke Head 1 Radial Spoke Head 2 Radial Spoke Head 3	Golgi Membrane Golgi Apparatus Membrane
	Molecular Function		Protein Binding Sulfotransferase Activity [heparan Sulfate]-glucosamine 3-sulfotransferase Activity Transferase Activity 3'-phosphoadenosine 5'-phosphosulfate Binding
	Biological Process	Cilium Movement Epithelial Cilium Movement Involved In Extracellular Fluid Movement Cell Projection Organization Axoneme Assembly Establishment Of Localization In Cell Cilium Assembly Cilium Movement Involved In Cell Motility Radial Spoke Assembly Maintenance Of Ciliary Planar Beating Movement Pattern	Protein Sulfation Heparan Sulfate Proteoglycan Biosynthetic Process Regulation Of Viral Entry Into Host Cell Negative Regulation Of Coagulation
Pathways			HS-GAG biosynthesis
Drugs
Diseases		Primary ciliary dyskinesia, including: Primary ciliary dyskinesia; Kartagener syndrome
GWAS			Body mass index ( 25673413) Cognitive decline rate in late mild cognitive impairment ( 26252872) Daytime nap ( 33568662) Gray matter volume (schizophrenia interaction) ( 24086445)
Interacting Genes
Entrez ID		345895	222537
HPRD ID		18005	13674
Ensembl ID		ENSG00000111834	ENSG00000249853
Uniprot IDs		B3KTA9 Q5TD94	Q8IZT8
PDB IDs		8J07	3BD9 7SCD 7SCE
Enriched GO Terms of Interacting Partners?		ATP Export ATP Transport Purine Nucleotide Transport Adenine Nucleotide Transport Monoatomic Cation Channel Activity Nucleotide Transport Carbohydrate Derivative Transport [heparan Sulfate]-glucosamine 3-sulfotransferase Activity Protein Sulfation Mitochondrial Protein Quality Control Organophosphate Ester Transport Voltage-gated Channel Activity Nucleobase-containing Compound Transport 3'-phosphoadenosine 5'-phosphosulfate Binding Mitochondrial Protein Catabolic Process Regulation Of Natural Killer Cell Cytokine Production Organic Anion Transport Sulfation Regulation Of Viral Entry Into Host Cell Heparan Sulfate Proteoglycan Biosynthetic Process	Radial Spoke Head 2 Maintenance Of Ciliary Planar Beating Movement Pattern Radial Spoke Head 1 Radial Spoke Assembly Radial Spoke Head 3 Radial Spoke Head Radial Spoke 9+2 Motile Cilium Regulation Of Cilium Movement Axoneme Assembly Extracellular Transport Epithelial Cilium Movement Involved In Extracellular Fluid Movement Regulation Of Microtubule-based Movement Microtubule Bundle Formation Axoneme Cilium Movement Involved In Cell Motility Cilium Movement Microtubule-based Transport Motile Cilium Regulation Of Microtubule-based Process Cilium Assembly Cilium Organization Plasma Membrane Bounded Cell Projection Assembly Cell Projection Assembly Microtubule-based Movement
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