DPP7 and ERGIC1

		DPP7	ERGIC1
Description		dipeptidyl peptidase 7	endoplasmic reticulum-golgi intermediate compartment 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Lysosome Golgi Apparatus Cytoplasmic Vesicle Vesicle Azurophil Granule Lumen Extracellular Exosome	Golgi Membrane Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Membrane COPII-coated ER To Golgi Transport Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	Aminopeptidase Activity Peptidase Activity Serine-type Peptidase Activity Dipeptidyl-peptidase Activity Hydrolase Activity Serine-type Exopeptidase Activity	Protein Binding
	Biological Process	Proteolysis Lysosomal Protein Catabolic Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Vesicle-mediated Transport
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS		Pursuit maintenance gain ( 29064472)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel) ( 23648065) Inflammatory bowel disease ( 28067908) Periodontitis (CDC/AAP) ( 24024966)
Interacting Genes		2 interacting genes: CFTR XRN1	2 interacting genes: EHHADH ERGIC3
Entrez ID		29952	57222
HPRD ID		07634	13836
Ensembl ID		ENSG00000176978	ENSG00000113719
Uniprot IDs		Q9UHL4	A0A8I5KPY8 Q969X5
PDB IDs		3JYH 3N0T 4EBB
Enriched GO Terms of Interacting Partners?		Epithelial Fluid Transport Fluid Transport Transepithelial Transport Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Granulocyte Macrophage Colony-stimulating Factor Receptor Binding Determination Of Stomach Left/right Asymmetry Determination Of Intestine Left/right Asymmetry Cellular Response To Puromycin Cellular Response To Cycloheximide Positive Regulation Of Anion Channel Activity Response To Purine-containing Compound Response To Lipid Positive Regulation Of Enamel Mineralization Positive Regulation Of Monoatomic Anion Transport Granulocyte-macrophage Colony-stimulating Factor Signaling Pathway Granulocyte Macrophage Colony-stimulating Factor Receptor Complex Response To Silicon Dioxide Maintenance Of Animal Organ Identity Ciliary Inversin Compartment 5'-3' RNA Exonuclease Activity Cellular Response To Oxygen-containing Compound Transepithelial Water Transport Determination Of Pancreatic Left/right Asymmetry Response To Cycloheximide Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Response To Ketone Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Positive Regulation Of Interleukin-23 Production Histamine Secretion Ureter Development Determination Of Digestive Tract Left/right Asymmetry Convergent Extension Involved In Gastrulation Determination Of Liver Left/right Asymmetry Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Response To Alcohol Neutrophil Differentiation G-quadruplex RNA Binding Amelogenesis Histamine Transport Atrial Septum Development G-quadruplex DNA Binding ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Regulation Of Interleukin-23 Production 5'-3' Exonuclease Activity
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