GPSM2 and CLCC1

		GPSM2	CLCC1
Description		G protein signaling modulator 2	chloride channel CLIC like 1
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Cytoplasm Centrosome Cytosol Cytoskeleton Plasma Membrane Cell Cortex Postsynaptic Density Membrane Lateral Plasma Membrane Protein-containing Complex Mitotic Spindle Pole Lateral Cell Cortex Cell Cortex Region	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Chloride Channel Complex Mitochondria-associated Endoplasmic Reticulum Membrane Contact Site
	Molecular Function	Nucleotide Binding G-protein Alpha-subunit Binding GDP-dissociation Inhibitor Activity Protein Binding Protein Domain Specific Binding GTPase Regulator Activity Identical Protein Binding Dynein Complex Binding	Chloride Channel Activity Protein Binding
	Biological Process	Establishment Of Mitotic Spindle Orientation Mitotic Spindle Organization G Protein-coupled Receptor Signaling Pathway Response To Light Intensity Cell Division Maintenance Of Centrosome Location Regulation Of Mitotic Spindle Organization Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Positive Regulation Of Protein Localization To Cell Cortex Positive Regulation Of Spindle Assembly	Monoatomic Ion Transport Chloride Transport Endoplasmic Reticulum Calcium Ion Homeostasis Monoatomic Ion Transmembrane Transport Chloride Transmembrane Transport
Pathways		G alpha (i) signalling events
Drugs
Diseases
GWAS		Fat distribution (HIV) ( 21897333)	Fat distribution (HIV) ( 21897333) Recurrent major depressive disorder ( 29317602)
Interacting Genes		17 interacting genes: AGR2 ARHGEF40 DLG4 FXR1 FXR2 GAS2L1 GLIS2 GNAI1 GNAI2 GNAI3 GNAO1 HRAS INSC LRRC8E NRIP1 NUMA1 WHRN	1 interacting genes: OGT
Entrez ID		29899	23155
HPRD ID		06609	17471
Ensembl ID		ENSG00000121957	ENSG00000121940
Uniprot IDs		B4DIF1 P81274	A0A6Q8PG14 Q96S66
PDB IDs		3SF4 4WND 4WNE 4WNF 4WNG 5A6C 6HC2
Enriched GO Terms of Interacting Partners?		Guanyl Nucleotide Binding G-protein Beta/gamma-subunit Complex Binding Regulation Of Long-term Neuronal Synaptic Plasticity Heterotrimeric G-protein Complex Regulation Of Neuronal Synaptic Plasticity Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway G Protein-coupled Serotonin Receptor Binding Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Adenylate Cyclase Regulator Activity Modulation Of Chemical Synaptic Transmission GTPase Activity Ciliary Basal Body Positive Regulation Of Protein Localization To Cell Cortex Regulation Of Protein Localization To Cell Periphery GTP Binding Regulation Of Protein Localization To Cell Cortex Positive Regulation Of Long-term Neuronal Synaptic Plasticity Adenylate Cyclase-inhibiting Serotonin Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Regulation Of Synaptic Plasticity G Protein Activity G Protein-coupled Receptor Binding GDP Binding Positive Regulation Of Protein Localization To Cell Periphery Cell Division Regulation Of Biological Quality Dendrite Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Translation Regulator Activity Regulation Of Cell Communication Regulation Of Signaling G Protein-coupled Serotonin Receptor Signaling Pathway Regulation Of Protein Localization Cytoskeletal Anchor Activity Cytoplasm Microtubule Plus-end Dentate Gyrus Development Neuron Projection Negative Regulation Of Secretion By Cell Regulation Of Microtubule Cytoskeleton Organization Negative Regulation Of Secretion P2Y1 Nucleotide Receptor Binding Negative Regulation Of Transport Cell Cortex Negative Regulation Of Insulin Secretion Positive Regulation Of Metabolic Process Regulation Of Mitotic Spindle Organization Midbody Positive Regulation Of Protein Localization Negative Regulation Of Peptide Secretion	Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Regulation Of Transcription By Glucose Cellular Response To Nutrient Regulation Of Glycolytic Process Protein Localization To Lysosome Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Regulation Of Carbohydrate Catabolic Process Positive Regulation Of TORC1 Signaling Regulation Of Protein Localization TORC1 Signaling Detection Of Hot Stimulus Involved In Thermoception Carbohydrate Response Element Binding Regulation Of ATP Metabolic Process TOR Signaling Regulation Of Purine Nucleotide Metabolic Process Positive Regulation Of TOR Signaling Growth Hormone Receptor Activity Protein Localization To Vacuole Positive Regulation Of Lipid Biosynthetic Process Regulation Of TORC1 Signaling Positive Regulation Of Protein Localization Lateral Cell Cortex ADP:phosphate Antiporter Activity Response To Nutrient Levels Growth Hormone Receptor Complex Protein O-acetylglucosaminyltransferase Activity Cell Cortex Region ATP:phosphate Antiporter Activity Regulation Of Generation Of Precursor Metabolites And Energy Positive Regulation Of Lipid Metabolic Process Adenine Nucleotide Transmembrane Transporter Activity Response To Cycloheximide Response To Insulin Regulation Of TOR Signaling Non-canonical Inflammasome Complex Assembly Regulation Of Protein Localization To Cell Periphery Protein Localization To Organelle Response To Nutrient Ragulator Complex Detection Of Temperature Stimulus Involved In Thermoception Regulation Of Microtubule Cytoskeleton Organization Anterior Commissure Morphogenesis Maintenance Of Centrosome Location Positive Regulation Of Protein Localization To Cell Cortex Glucose Mediated Signaling Pathway Regulation Of Biological Quality
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