RBM15B and ITIH1

		RBM15B	ITIH1
Description		RNA binding motif protein 15B	inter-alpha-trypsin inhibitor heavy chain 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nucleoplasm Nucleolus Nuclear Speck RNA N6-methyladenosine Methyltransferase Complex	Extracellular Region Extracellular Matrix Extracellular Exosome Blood Microparticle
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding	Serine-type Endopeptidase Inhibitor Activity Calcium Ion Binding Protein Binding Hyaluronic Acid Binding Carbohydrate Binding Peptidase Inhibitor Activity
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome RNA Methylation MRNA Processing MRNA Export From Nucleus Nucleocytoplasmic Transport RNA Splicing Dosage Compensation By Inactivation Of X Chromosome Negative Regulation Of DNA-templated Transcription	Hyaluronan Metabolic Process
Pathways
Drugs			Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29679657) Lipoprotein (a) levels ( 33730874)	A body shape index ( 34021172) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972 34002096 33263727 31043756 19416921) Body mass index ( 25673413) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cortical surface area (MOSTest) ( 32665545) General cognitive ability ( 29844566) Glaucoma (primary open-angle) ( 25173105) Osteoarthritis (hip) ( 30374069) Pulse pressure ( 30578418) Schizophrenia ( 29483656 25056061 23974872) Schizophrenia, schizoaffective disorder or bipolar disorder ( 24166486) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for body mass index ( 28448500 34021172) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for body mass index ( 28448500)
Interacting Genes		11 interacting genes: ATP6V0D2 CDC23 DVL3 EGR2 ERBB2 NAV2 NXF1 RNF10 SRPK2 TNNC1 TRIM54	3 interacting genes: HSP90AA1 PIK3CA SOX4
Entrez ID		29890	3697
HPRD ID		11486	00927
Ensembl ID		ENSG00000259956	ENSG00000055957
Uniprot IDs		Q8NDT2	B7Z8B6 P19827
PDB IDs			6FPY 6FPZ
Enriched GO Terms of Interacting Partners?		Motor Neuron Axon Guidance Peripheral Nervous System Development Regulation Of Nervous System Process Positive Regulation Of Myelination Rhythmic Behavior Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Rhombomere 5 Structural Organization Rhombomere 3 Structural Organization Rhombomere 3 Formation Rhombomere 5 Formation Regulation Of Myelination Negative Regulation Of Synaptic Vesicle Clustering Regulation Of Muscle Filament Sliding Speed Glossopharyngeal Nerve Development Regulation Of Systemic Arterial Blood Pressure By Baroreceptor Feedback Vagus Nerve Development	Regulation Of Cell Projection Assembly Regulation Of Apoptotic Process Intracellular Transport Nuclear Export Nuclear Transport Nucleocytoplasmic Transport Protein Stabilization Endocytic Vesicle Lumen MRNA Binding Positive Regulation Of Lamellipodium Organization Positive Regulation Of Lamellipodium Assembly Regulation Of Lamellipodium Assembly Regulation Of Programmed Cell Death Cellular Localization Establishment Of Localization In Cell Regulation Of Lamellipodium Organization Protein Folding Chaperone Positive Regulation Of Establishment Of Protein Localization Epidermal Growth Factor Receptor Signaling Pathway Cellular Response To Glucose Stimulus CTP Binding DATP Binding Regulation Of Protein Localization Cellular Response To Virus Regulation Of Protein Stability Cellular Response To Carbohydrate Stimulus ERBB Signaling Pathway Response To Virus RNA Export From Nucleus Striated Muscle Contraction Regulation Of Gene Expression Positive Regulation Of Immune System Process Intracellular Glucose Homeostasis Regulation Of Macromolecule Biosynthetic Process Protein Transport Phospholipase D Activator Activity Positive Regulation Of Protein Localization Neurofibrillary Tangle Assembly UTP Binding Sulfonylurea Receptor Binding Unfolded Protein Binding Regulation Of Organelle Organization Response To Biphenyl Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Rho GDP-dissociation Inhibitor Binding Response To Butyrate Cellular Response To Hydrostatic Pressure Intracellular Chemical Homeostasis Regulation Of Establishment Of Protein Localization Response To Glucose
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