RBM15B and AMT

		RBM15B	AMT
Description		RNA binding motif protein 15B	aminomethyltransferase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nucleoplasm Nucleolus Nuclear Speck RNA N6-methyladenosine Methyltransferase Complex	Nucleoplasm Mitochondrion Mitochondrial Matrix Glycine Cleavage Complex
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding	Aminomethyltransferase Activity Protein Binding Transaminase Activity Transferase Activity
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome RNA Methylation MRNA Processing MRNA Export From Nucleus Nucleocytoplasmic Transport RNA Splicing Dosage Compensation By Inactivation Of X Chromosome Negative Regulation Of DNA-templated Transcription	Glycine Catabolic Process Glycine Decarboxylation Via Glycine Cleavage System
Pathways			Glycine degradation
Drugs			Tetrahydrofolic acid NADH 5-methyltetrahydrofolic acid
Diseases			Nonketotic hyperglycinemia; Glycine encephalopathy (GCE)
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29679657) Lipoprotein (a) levels ( 33730874)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive function ( 25644384) Coronary artery disease ( 29212778) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Depressive symptom (depressed mood) (binary trait) ( 31530331) Depressive symptoms (binary sum-score) ( 31530331) Extremely high intelligence ( 29520040) Gut microbiota (functional units) ( 27694959) Inflammatory bowel disease ( 28067908) Regular attendance at a religious group ( 29970889) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)
Interacting Genes		11 interacting genes: ATP6V0D2 CDC23 DVL3 EGR2 ERBB2 NAV2 NXF1 RNF10 SRPK2 TNNC1 TRIM54	2 interacting genes: PDLIM4 VAC14
Entrez ID		29890	275
HPRD ID		11486	01997
Ensembl ID		ENSG00000259956	ENSG00000145020
Uniprot IDs		Q8NDT2	P48728
PDB IDs			1WSR 1WSV
Enriched GO Terms of Interacting Partners?		Motor Neuron Axon Guidance Peripheral Nervous System Development Regulation Of Nervous System Process Positive Regulation Of Myelination Rhythmic Behavior Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Rhombomere 5 Structural Organization Rhombomere 3 Structural Organization Rhombomere 3 Formation Rhombomere 5 Formation Regulation Of Myelination Negative Regulation Of Synaptic Vesicle Clustering Regulation Of Muscle Filament Sliding Speed Glossopharyngeal Nerve Development Regulation Of Systemic Arterial Blood Pressure By Baroreceptor Feedback Vagus Nerve Development
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