ALG5 and SOHLH2

		ALG5	SOHLH2
Description		ALG5 dolichyl-phosphate beta-glucosyltransferase	spermatogenesis and oogenesis specific basic helix-loop-helix 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Cytoplasmic Side Of Rough Endoplasmic Reticulum Membrane	Chromatin Nucleus Cytoplasm
	Molecular Function	Dolichyl-phosphate Beta-glucosyltransferase Activity Protein Binding Transferase Activity Glycosyltransferase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Homodimerization Activity Protein Heterodimerization Activity Protein Dimerization Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	Protein Glycosylation Protein N-linked Glycosylation Dolichol-linked Oligosaccharide Biosynthetic Process Determination Of Left/right Symmetry Protein N-linked Glycosylation Via Asparagine	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Spermatogenesis Oocyte Differentiation Cell Differentiation Oogenesis
Pathways		Synthesis of dolichyl-phosphate-glucose
Drugs
Diseases
GWAS		Interleukin-10 levels ( 22205395)	Cocaine dependence ( 31212010) Economic and political preferences ( 22566634) Glucose homeostasis traits ( 25524916)
Interacting Genes			1 interacting genes: ELOA2
Entrez ID		29880	54937
HPRD ID		05193	07910
Ensembl ID		ENSG00000120697	ENSG00000120669
Uniprot IDs		Q9Y673	Q9NX45
PDB IDs
Enriched GO Terms of Interacting Partners?		Carbohydrate Binding Pentose-phosphate Shunt, Oxidative Branch Pentose Biosynthetic Process D-gluconate Metabolic Process Phosphogluconate Dehydrogenase (decarboxylating) Activity Cellular Response To Vitamin K Bone Regeneration Oocyte Differentiation Response To Vitamin K Pentose Metabolic Process Carboxylic Acid Binding Regulation Of Opsonization Serine-type Endopeptidase Complex Positive Regulation Of Opsonization Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Complement Activation, Lectin Pathway Pentose-phosphate Shunt Negative Regulation Of Substrate Adhesion-dependent Cell Spreading	Dolichyl-phosphate Beta-glucosyltransferase Activity Elongin Complex Cytoplasmic Side Of Rough Endoplasmic Reticulum Membrane Protein N-linked Glycosylation Via Asparagine Dolichol-linked Oligosaccharide Biosynthetic Process
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