ATL3 and TMEM216

		ATL3	TMEM216
Description		atlastin GTPase 3	transmembrane protein 216
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Membrane	Cytoplasm Cytosol Cytoskeleton Cilium Membrane Ciliary Transition Zone MKS Complex Cell Projection
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity Identical Protein Binding GTPase-dependent Fusogenic Activity	Protein Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Endoplasmic Reticulum Organization Golgi Organization Endoplasmic Reticulum Membrane Fusion Protein Homooligomerization Endoplasmic Reticulum Tubular Network Membrane Organization	Cell Projection Organization Cilium Assembly Non-motile Cilium Assembly
Pathways			Anchoring of the basal body to the plasma membrane
Drugs
Diseases			Joubert syndrome
GWAS
Interacting Genes		2 interacting genes: APP OGT	1 interacting genes: MCM3AP
Entrez ID		25923	51259
HPRD ID		13170	14439
Ensembl ID		ENSG00000184743	ENSG00000187049
Uniprot IDs		B4DXC4 F5H6I7 Q6DD88	J3QT25 Q9P0N5
PDB IDs		5VGR 6XJO
Enriched GO Terms of Interacting Partners?		Amyloid-beta Complex Regulation Of ATP Metabolic Process Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Regulation Of Carbohydrate Catabolic Process Regulation Of Glycolytic Process Amylin Binding Regulation Of Purine Nucleotide Metabolic Process Positive Regulation Of Toll Signaling Pathway Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Acetylcholine Receptor Activator Activity PTB Domain Binding Regulation Of Synapse Assembly Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Hemopoiesis Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Regulation Of Generation Of Precursor Metabolites And Energy Protein O-acetylglucosaminyltransferase Activity Positive Regulation Of Proteolysis Regulation Of Cell Junction Assembly Regulation Of Spontaneous Synaptic Transmission Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Regulation Of Toll Signaling Pathway Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Alpha DNA Polymerase:primase Complex DNA Replication, Synthesis Of Primer Cell Projection
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