EEF1AKMT3 and DNAI1

		EEF1AKMT3	DNAI1
Description		EEF1A lysine methyltransferase 3	dynein axonemal intermediate chain 1
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GO Annotations	Cellular Component	Nucleoplasm Chromosome Cytoplasm Centrosome Cytosol Cytoskeleton Protein-containing Complex	Extracellular Region Cytoplasm Centrosome Cytoskeleton Microtubule Cilium Microtubule Cytoskeleton Dynein Complex Outer Dynein Arm Cell Projection Glial Cell Projection 9+2 Motile Cilium Dynein Axonemal Particle
	Molecular Function	Protein Binding Methyltransferase Activity Protein-lysine N-methyltransferase Activity Transferase Activity Heat Shock Protein Binding	Cytoskeletal Motor Activity Protein Binding Dynein Light Chain Binding Dynein Heavy Chain Binding
	Biological Process	Peptidyl-lysine Methylation Methylation	Cilium Movement Epithelial Cilium Movement Involved In Extracellular Fluid Movement Determination Of Left/right Symmetry Heart Development Insulin Receptor Signaling Pathway Cell Projection Organization Flagellated Sperm Motility Outer Dynein Arm Assembly
Pathways
Drugs
Diseases			Primary ciliary dyskinesia, including: Primary ciliary dyskinesia; Kartagener syndrome
GWAS			Anti-drug antibodies in autoimmune disease (time to event) ( 33125391)
Interacting Genes		5 interacting genes: ALS2CL MAGEB4 MSRB3 VAC14 ZIC1	2 interacting genes: PAFAH1B1 SQSTM1
Entrez ID		25895	27019
HPRD ID		08532	05080
Ensembl ID		ENSG00000123427	ENSG00000122735
Uniprot IDs		Q96AZ1	A0A087WWV9 A0A140VJI0 Q9UI46
PDB IDs		4QPN	8J07
Enriched GO Terms of Interacting Partners?			Autophagy Of Mitochondrion DNA-templated Transcription Positive Regulation Of Macrophage Apoptotic Process Nucleobase-containing Compound Biosynthetic Process Intracellular Signal Transduction Negative Regulation Of Protein Ubiquitination Stem Cell Division Protein K63-linked Ubiquitination Autophagy Cell Population Proliferation Ligase Inhibitor Activity Negative Regulation Of Post-translational Protein Modification Apoptotic Process Involved In Mammary Gland Involution Stem Cell Population Maintenance Catabolic Process Glycine Decarboxylation Via Glycine Cleavage System Response To Lipoic Acid Glycine Cleavage Complex Glycine Dehydrogenase (decarboxylating) Activity Pyridoxal Binding Glycine Catabolic Process Response To Methylamine Limb Morphogenesis Cumulus Cell Differentiation Natriuretic Peptide Receptor Activity Vestibulocochlear Nerve Maturation Nerve Maturation C-di-GMP Signaling Granulosa Cell Differentiation Activation Of Meiosis Involved In Egg Activation Neuromuscular Process Gastric Emptying Negative Regulation Of Oocyte Maturation Microtubule Sliding 1-alkyl-2-acetylglycerophosphocholine Esterase Complex Forebrain Development Astral Microtubule Hippocampus Development Microtubule Cytoskeleton Organization Involved In Establishment Of Planar Polarity Central Region Of Growth Cone Neural Plate Development Central Nervous System Segmentation Determination Of Left/right Asymmetry In Nervous System Mitophagy Brown Fat Cell Proliferation Amphisome Atg12 Transferase Activity Atg12 Conjugating Enzyme Activity Maintenance Of Cell Number Positive Regulation Of Apoptotic Process Involved In Mammary Gland Involution
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