PPIL2 and ZDHHC8

		PPIL2	ZDHHC8
Description		peptidylprolyl isomerase like 2	zDHHC palmitoyltransferase 8
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Golgi Lumen Plasma Membrane Catalytic Step 2 Spliceosome	Golgi Membrane Mitochondrion Golgi Apparatus Cytosol Membrane Mitochondrial Membrane Postsynapse Glutamatergic Synapse
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Ubiquitin-protein Transferase Activity Protein Binding Transferase Activity Ubiquitin-ubiquitin Ligase Activity Ubiquitin Protein Ligase Activity	Palmitoyltransferase Activity Transferase Activity Acyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity
	Biological Process	Protein Polyubiquitination MRNA Processing Protein Folding RNA Splicing Protein Ubiquitination Protein Localization To Plasma Membrane	Locomotory Behavior Positive Regulation Of Cholesterol Efflux Peptidyl-L-cysteine S-palmitoylation High-density Lipoprotein Particle Assembly Host-mediated Activation Of Viral Process Regulation Of Postsynapse Assembly Positive Regulation Of Protein Localization To Plasma Membrane
Pathways		Basigin interactions mRNA Splicing - Major Pathway	HDL assembly Maturation of spike protein
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Type 1 diabetes autoantibodies in high risk HLA genotype individuals (time to event) ( 29310926) Type 1 diabetes in high risk HLA genotype individuals (time to event) ( 29310926)
Interacting Genes		11 interacting genes: APP BSG CALM1 CEBPA CRNKL1 HSP90AA1 PLK1 PRCC SNAI1 TRIM23 ZNF830
Entrez ID		23759	29801
HPRD ID		08472	12298
Ensembl ID		ENSG00000100023	ENSG00000099904
Uniprot IDs		A0A7P0TBL3 A8K0I0 Q13356	Q9ULC8
PDB IDs		1ZKC 7ABI 7DVQ 7QTT 8CH6 8I0P 8I0R 8I0S 8I0T
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Catabolic Process Positive Regulation Of Protein Localization Positive Regulation Of Catabolic Process Regulation Of Cell Cycle Response To Metal Ion Notch Signaling Pathway Regulation Of Protein Catabolic Process Regulation Of Protein Localization To Nucleus Myelin Sheath Positive Regulation Of Proteolysis Amyloid-beta Complex Regulation Of Cell Junction Assembly Growth Cone Lamellipodium Positive Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Blood Circulation Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Neuron Recognition Regulation Of Protein Localization Positive Regulation Of Nitric Oxide Metabolic Process Positive Regulation Of Protein Transport Spindle Microtubule Cell Cycle G2/M Phase Transition G2/M Transition Of Mitotic Cell Cycle RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding CTP Binding DATP Binding Mitotic G2/M Transition Checkpoint Acetylcholine Receptor Activator Activity PTB Domain Binding Developmental Growth Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Establishment Of Protein Localization Positive Regulation Of Protein Metabolic Process Reproductive Process Positive Regulation Of Interleukin-6 Production Regulation Of Proteolysis Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Apoptotic Process Protein-containing Complex Regulation Of Calcium-mediated Signaling Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Transport Positive Regulation Of Protein Import	F-actin Monooxygenase Activity Neuregulin Receptor Activity Ganglioside GT1b Binding Ganglioside GM1 Binding
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