LARP4B and ADARB2

		LARP4B	ADARB2
Description		La ribonucleoprotein 4B	adenosine deaminase RNA specific B2 (inactive)
Image			No pdb structure
GO Annotations	Cellular Component	Nucleolus Cytoplasm Cytosol Cytoplasmic Stress Granule Membrane	Nucleus Nucleolus Cytoplasm
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA 3'-UTR Binding Protein Binding	RNA Binding Double-stranded RNA Binding Double-stranded RNA Adenosine Deaminase Activity Single-stranded RNA Binding Adenosine Deaminase Activity TRNA-specific Adenosine Deaminase Activity Hydrolase Activity Deaminase Activity Metal Ion Binding
	Biological Process	Regulation Of Translation Positive Regulation Of Translation Positive Regulation Of 3'-UTR-mediated MRNA Stabilization	Adenosine To Inosine Editing RNA Processing MRNA Processing
Pathways
Drugs
Diseases
GWAS		Basophil count ( 32888494) Basophil percentage of granulocytes ( 27863252) Basophil percentage of white cells ( 27863252 32888494) Bisphosphonate-associated atypical femoral fracture ( 31006051) Blood urea nitrogen levels ( 31152163) Chronic kidney disease ( 31152163) Chronotype ( 30696823) Estimated glomerular filtration rate ( 31015462 31451708 31152163) Estimated glomerular filtration rate in non-diabetics ( 31451708) Femur bone mineral density x serum urate levels interaction ( 34046847) Neutrophil percentage of granulocytes ( 27863252) Prostate cancer ( 29892016) Prostate cancer (advanced) ( 29892016) Prostate cancer (early onset) ( 29892016) Reticulocyte fraction of red cells ( 32888494) Sum eosinophil basophil counts ( 27863252) White blood cell count (basophil) ( 27863252)	Accelerated cognitive decline after conversion of mild cognitive impairment to Alzheimer's disease (Alzhiemer's diagnosis trajectory interaction) ( 28560309) Adverse response to drug ( 30420678) Blood pressure (smoking interaction) ( 25189868) Emphysema-related traits ( 20709820) Familial lung cancer ( 29924316) Hip circumference ( 28552196) Hippocampal volume in mild cognitive impairment ( 29274321) Menarche (age at onset) ( 25231870) Metabolite levels ( 23823483) Quantitative traits ( 19197348) Radiation response ( 20923822) Systolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
Interacting Genes		7 interacting genes: ATXN1L C1QTNF9 DMRTB1 MAGED1 OGT PABPC1 RBPMS
Entrez ID		23185	105
HPRD ID		13787	09070
Ensembl ID		ENSG00000107929	ENSG00000185736
Uniprot IDs		Q92615	Q9NS39
PDB IDs		3PTH
Enriched GO Terms of Interacting Partners?		Dimethylallyl Diphosphate Biosynthetic Process Isopentenyl-diphosphate Delta-isomerase Activity Intramolecular Oxidoreductase Activity Isopentenyl Diphosphate Biosynthetic Process Isopentenyl Diphosphate Metabolic Process Isoprenoid Biosynthetic Process Cholesterol Biosynthetic Process Sterol Biosynthetic Process Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly	Positive Regulation Of 3'-UTR-mediated MRNA Stabilization
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