RRP1B and CLDN14

		RRP1B	CLDN14
Description		ribosomal RNA processing 1B	claudin 14
Image			No pdb structure
GO Annotations	Cellular Component	Euchromatin Heterochromatin Granular Component Nucleus Nucleoplasm Chromosome Nucleolus Cytosol Preribosome, Small Subunit Precursor	Endoplasmic Reticulum Plasma Membrane Bicellular Tight Junction Membrane Anchoring Junction
	Molecular Function	Transcription Coactivator Activity RNA Binding Protein Binding	Structural Molecule Activity Protein Binding Identical Protein Binding
	Biological Process	RRNA Processing MRNA Processing Apoptotic Process RNA Splicing Negative Regulation Of GTPase Activity Positive Regulation Of Apoptotic Process Regulation Of RNA Splicing Host-mediated Activation Of Viral Transcription Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Virus	Cell Adhesion Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Protein-containing Complex Assembly Bicellular Tight Junction Assembly
Pathways			Tight junction interactions
Drugs
Diseases			Deafness, autosomal recessive
GWAS		Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Coronary artery disease ( 29212778) Diastolic blood pressure ( 27618447 28135244) Mean corpuscular hemoglobin ( 27863252) Refractive error ( 32231278) Systolic blood pressure ( 27618447)	Blood urea nitrogen levels ( 31152163) Bone mineral density ( 24249740) Estimated glomerular filtration rate ( 31015462 31152163) Femur bone mineral density x serum urate levels interaction ( 34046847) Glomerular filtration rate ( 29403010) Heel bone mineral density ( 30598549) Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Kidney stones ( 26272126 31729369 19561606) Obsessive-compulsive traits ( 33531474) Red blood cell count ( 32888494) Serum parathyroid hormone levels ( 27927781) Urate levels ( 31578528) Urinary electrolytes (magnesium/calcium ratio) ( 27915449) Urolithiasis ( 30975718)
Interacting Genes		6 interacting genes: CSNK2A1 LSM1 OGT PPP1CA PPP1CC SRPK2	4 interacting genes: CTXN3 MAL PLEKHA1 PLLP
Entrez ID		23076	23562
HPRD ID		10009	05727
Ensembl ID		ENSG00000160208	ENSG00000159261
Uniprot IDs		Q14684	O95500
PDB IDs		7T0Y
Enriched GO Terms of Interacting Partners?		Rhythmic Process Circadian Regulation Of Gene Expression PTW/PP1 Phosphatase Complex Regulation Of Translational Initiation Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA MRNA Methylguanosine-cap Decapping Circadian Rhythm RNA Decapping Sin3-type Complex Entrainment Of Circadian Clock By Photoperiod Protein Phosphatase 1 Binding Photoperiodism Entrainment Of Circadian Clock Presynapse Negative Regulation Of Translational Initiation Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Double-strand Break Repair Via Nonhomologous End Joining Protein Modification Process Glycogen Metabolic Process Regulation Of Carbohydrate Catabolic Process Protein Metabolic Process Energy Reserve Metabolic Process Polysaccharide Metabolic Process Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Phosphatase Activity Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Carbohydrate Metabolic Process Regulation Of Translation Protein Dephosphorylation Protein Serine/threonine Phosphatase Activity Protein Localization To Vacuole Macromolecule Metabolic Process RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Regulation Of Glucose Metabolic Process Nuclear-transcribed MRNA Catabolic Process Regulation Of Circadian Rhythm Protein O-linked Glycosylation Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Negative Regulation Of Protein Catabolic Process Positive Regulation Of Termination Of RNA Polymerase II Transcription, Poly(A)-coupled Protein O-acetylglucosaminyltransferase Activity MRNA Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteolysis Positive Regulation Of Termination Of DNA-templated Transcription Dephosphorylation	Structural Constituent Of Myelin Sheath Protein Insertion Into Plasma Membrane Myelination Axon Ensheathment Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane Regulation Of Transcytosis Membrane Raft Polarization Positive Regulation Of Protein Folding Peptide-O-fucosyltransferase Activity Protein Localization To Paranode Region Of Axon Compact Myelin Peptidase Activator Activity Involved In Apoptotic Process Protein O-linked Glycosylation Via Fucose Membrane Raft Distribution Granular Component Protein Localization To Axon Schmidt-Lanterman Incisure Membrane Raft Membrane Raft Localization Regulation Of Protein Folding Fucosylation Fucosyltransferase Activity Luteinization Leydig Cell Differentiation
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?