EMC1 and PADI2

		EMC1	PADI2
Description		ER membrane protein complex subunit 1	peptidyl arginine deiminase 2
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Protein-containing Complex EMC Complex	Euchromatin Extracellular Region Nucleus Cytoplasm Cytosol Azurophil Granule Lumen Extracellular Exosome
	Molecular Function	Protein Binding Membrane Insertase Activity	Protein-arginine Deiminase Activity Calcium Ion Binding Hydrolase Activity Nuclear Estrogen Receptor Binding Protein Homodimerization Activity Metal Ion Binding Histone Arginine Deiminase Activity Histone H3R26 Arginine Deiminase Activity
	Biological Process	Protein Insertion Into ER Membrane By Stop-transfer Membrane-anchor Sequence Tail-anchored Membrane Protein Insertion Into ER Membrane	Chromatin Remodeling Substantia Nigra Development Estrogen Receptor Signaling Pathway Transcription Initiation-coupled Chromatin Remodeling Negative Regulation Of Chemokine-mediated Signaling Pathway Negative Regulation Of Lymphocyte Chemotaxis Cellular Response To Leukemia Inhibitory Factor
Pathways			Chromatin modifying enzymes Neutrophil degranulation
Drugs			Citrulline
Diseases
GWAS			A body shape index ( 34021172) Gut microbiota relative abundance (Ruminococcus belonging to family Lachnospiraceae) ( 33208821) Hemoglobin ( 32888494) Hip circumference adjusted for BMI ( 34021172) Prudent dietary pattern ( 28644415) Rheumatoid arthritis ( 30423114) Visceral fat ( 30942860) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172)
Interacting Genes			1 interacting genes: RIPK4
Entrez ID		23065	11240
HPRD ID		08306	06396
Ensembl ID		ENSG00000127463	ENSG00000117115
Uniprot IDs		H7C5A2 Q8N766	Q9Y2J8
PDB IDs		6WW7 6Z3W 7ADO 7ADP 8EOI 8J0N 8J0O 8S9S 9C7V	4N20 4N22 4N24 4N25 4N26 4N28 4N2A 4N2B 4N2C 4N2D 4N2E 4N2F 4N2G 4N2H 4N2I 4N2K 4N2L 4N2M 4N2N 9B96 9B97 9B98
Enriched GO Terms of Interacting Partners?			Histone H3R8 Arginine Deiminase Activity Histone H3R17 Arginine Deiminase Activity Histone H3R2 Arginine Deiminase Activity Histone H3R26 Arginine Deiminase Activity Histone Arginine Deiminase Activity Protein-arginine Deiminase Activity Protein Insertion Into ER Membrane By Stop-transfer Membrane-anchor Sequence EMC Complex Membrane Insertase Activity Tail-anchored Membrane Protein Insertion Into ER Membrane Protein Insertion Into ER Membrane Protein-containing Complex
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