TAPT1 and CLRN2

		TAPT1	CLRN2
Description		transmembrane anterior posterior transformation 1	clarin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Endoplasmic Reticulum Membrane Centrosome Cytosol Cytoskeleton Cilium Membrane Ciliary Basal Body Cell Projection	Plasma Membrane Membrane Stereocilium Bundle Cell Projection Stereocilium Membrane
	Molecular Function	Growth Hormone-releasing Hormone Receptor Activity	Protein Binding
	Biological Process	Ossification G Protein-coupled Receptor Signaling Pathway Neural Crest Cell Development Cell Projection Organization Cell Differentiation Positive Regulation Of Cilium Assembly Embryonic Skeletal System Development Cartilage Development Positive Regulation Of Cartilage Development Positive Regulation Of Bone Development	Sensory Perception Of Sound Inner Ear Auditory Receptor Cell Differentiation Auditory Receptor Cell Stereocilium Organization Stereocilium Maintenance
Pathways
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Glomerular filtration rate in chronic kidney disease ( 26420894) Systemic juvenile idiopathic arthritis ( 27927641)	Age-related hearing impairment ( 34108613) Metabolite levels ( 23823483)
Interacting Genes		2 interacting genes: SMAD1 SMURF1	12 interacting genes: ARL6IP6 CLDN5 CLEC2D FNDC9 KLRC1 LRRC25 NEMP1 SIT1 SSMEM1 STOM TEX29 VSIR
Entrez ID		202018	645104
HPRD ID		08290	19335
Ensembl ID		ENSG00000169762	ENSG00000249581
Uniprot IDs		B4DJJ3 Q6NXT6	A0PK11
PDB IDs
Enriched GO Terms of Interacting Partners?		I-SMAD Binding BMP Signaling Pathway Engulfment Of Target By Autophagosome Mesodermal Cell Fate Commitment Homomeric SMAD Protein Complex Osteoblast Fate Commitment Stereocilium Maintenance Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Anti-Mullerian Hormone Receptor Signaling Pathway Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Stereocilium Membrane Heteromeric SMAD Protein Complex SMAD Protein Complex DEAD/H-box RNA Helicase Binding Activin Receptor Binding Substrate Localization To Autophagosome	Membrane
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