TMEM201 and NPHP4

		TMEM201	NPHP4
Description		transmembrane protein 201	nephrocystin 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Spindle Pole Nucleus Nuclear Envelope Nuclear Inner Membrane Cytoplasm Cytoskeleton Membrane Spindle Pole Centrosome Nuclear Membrane Cortical Endoplasmic Reticulum	Nucleus Nucleoplasm Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Cell-cell Junction Bicellular Tight Junction Cilium Nuclear Body Photoreceptor Connecting Cilium Ciliary Transition Zone Ciliary Basal Body Cell Projection Anchoring Junction Ribbon Synapse Ciliary Base Non-motile Cilium Photoreceptor Distal Connecting Cilium
	Molecular Function	Protein Binding Lamin Binding Actin Filament Binding	Structural Molecule Activity Protein Binding
	Biological Process	Angiogenesis Nuclear Envelope Organization Nuclear Migration Positive Regulation Of Endothelial Cell Migration Fibroblast Migration Nuclear Migration Along Microtubule Centrosome Localization Protein Localization To Nuclear Envelope	Signal Transduction Visual Behavior Actin Cytoskeleton Organization Flagellated Sperm Motility Photoreceptor Cell Outer Segment Organization Photoreceptor Cell Maintenance Retina Development In Camera-type Eye Negative Regulation Of Canonical Wnt Signaling Pathway Cell-cell Adhesion Positive Regulation Of Bicellular Tight Junction Assembly Protein Localization To Ciliary Transition Zone
Pathways			Signaling by Hippo Anchoring of the basal body to the plasma membrane
Drugs
Diseases			Nephronophthisis-medullary cystic kidney disease, including; Nephronophthisis (NPH) ; Nephronophthisis-like nephropathy 1; Medullary cystic kidney disease 1; Medullary cystic kidney disease 2 (MSKD2) Senior-Loken syndrome
GWAS			Dimensional psychopathology (Positive) ( 29496196) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) QT interval ( 19305408) Response to taxane treatment (paclitaxel) ( 23006423)
Interacting Genes		23 interacting genes: CLEC17A CPLX4 CYB5R3 DNAJC1 EMD FATE1 FRMD3 GOLM2 GPR152 KCNJ9 LHFPL5 LMNA LRRC25 MFF MINAR1 NDUFAF2 PTPN5 SLC26A6 TMEM237 TMEM35A TMX2 UBC VEZT	2 interacting genes: NPHP1 RPGRIP1
Entrez ID		199953	261734
HPRD ID		17991	06238
Ensembl ID		ENSG00000188807	ENSG00000131697
Uniprot IDs		Q5SNT2	B3KW36 O75161
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Mitochondrial Outer Membrane	Photoreceptor Connecting Cilium
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