DNAH10 and RILPL2

		DNAH10	RILPL2
Description		dynein axonemal heavy chain 10	Rab interacting lysosomal protein like 2
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GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Axonemal Dynein Complex Microtubule Cilium Dynein Complex Cell Projection 9+2 Motile Cilium	Cytoplasm Centrosome Cytosol Cytoskeleton Cilium Membrane Ciliary Basal Body Cell Projection
	Molecular Function	Nucleotide Binding Microtubule Motor Activity ATP Binding Microtubule Binding Minus-end-directed Microtubule Motor Activity Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding	Protein Binding Small GTPase Binding Identical Protein Binding Protein Dimerization Activity Dynein Light Intermediate Chain Binding
	Biological Process	Microtubule-based Process Microtubule-based Movement Cilium Movement Involved In Cell Motility	Epithelial Cell Morphogenesis Protein Transport Cilium Assembly Protein Transport From Ciliary Membrane To Plasma Membrane
Pathways
Drugs
Diseases
GWAS		A body shape index ( 34021172) Adiponectin levels ( 22479202 31178129) Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) Appendicular lean mass ( 33097823) Atrial fibrillation ( 29892015) Coronary artery disease ( 29212778) Fasting insulin ( 34059833) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference adjusted for BMI ( 34021172 28552196) Hip index ( 34021172) Low density lipoprotein cholesterol levels ( 32154731) Lymphocyte count ( 32888494 27863252) Osteoarthritis (hip) ( 23989986) Reticulocyte count ( 27863252 32888494) Reticulocyte fraction of red cells ( 32888494) Visceral adipose tissue adjusted for BMI ( 22589738) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 25673412 28448500 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 30389748 26426971 34021172) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 28448500) White blood cell count ( 32888494)	A body shape index ( 34021172) Alanine aminotransferase levels ( 33547301) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Educational attainment ( 25201988) Height ( 28552196) High density lipoprotein cholesterol levels ( 29403010) Hip circumference adjusted for BMI ( 34021172) Lymphocyte count ( 27863252) Schizophrenia ( 25056061 29483656 23974872) Tourette syndrome ( 30818990) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 26426971 34021172) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		1 interacting genes: LINC00839	2 interacting genes: HEXD TUBB3
Entrez ID		196385	196383
HPRD ID		13473	10084
Ensembl ID		ENSG00000197653	ENSG00000150977
Uniprot IDs		A0A669KB38 B0I1S1 Q8IVF4	Q969X0
PDB IDs		8J07	6RIR 6SQ2 7LWB
Enriched GO Terms of Interacting Partners?		Protein Transport From Ciliary Membrane To Plasma Membrane Glutaminyl-tRNAGln Biosynthesis Via Transamidation Glutaminyl-tRNA Synthase (glutamine-hydrolyzing) Activity Carbon-nitrogen Ligase Activity, With Glutamine As Amido-N-donor Glutamyl-tRNA(Gln) Amidotransferase Complex	Netrin Receptor Binding Dorsal Root Ganglion Development Beta-N-acetylhexosaminidase Activity Hexosaminidase Activity Microtubule Netrin-activated Signaling Pathway Ganglion Development Minus-end-directed Microtubule Motor Activity Axonemal Dynein Complex Peptide Binding Microtubule-based Process 9+2 Motile Cilium Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding Dynein Complex Hydrolase Activity, Hydrolyzing O-glycosyl Compounds Microtubule Motor Activity
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