RILPL2 and DNAH10

		RILPL2	DNAH10
Description		Rab interacting lysosomal protein like 2	dynein axonemal heavy chain 10
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GO Annotations	Cellular Component	Cytoplasm Centrosome Cytosol Cytoskeleton Cilium Membrane Ciliary Basal Body Cell Projection	Cytoplasm Cytoskeleton Axonemal Dynein Complex Microtubule Cilium Dynein Complex Cell Projection 9+2 Motile Cilium
	Molecular Function	Protein Binding Small GTPase Binding Identical Protein Binding Protein Dimerization Activity Dynein Light Intermediate Chain Binding	Nucleotide Binding Microtubule Motor Activity ATP Binding Microtubule Binding Minus-end-directed Microtubule Motor Activity Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding
	Biological Process	Epithelial Cell Morphogenesis Protein Transport Cilium Assembly Protein Transport From Ciliary Membrane To Plasma Membrane	Microtubule-based Process Microtubule-based Movement Cilium Movement Involved In Cell Motility
Pathways
Drugs
Diseases
GWAS		A body shape index ( 34021172) Alanine aminotransferase levels ( 33547301) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Educational attainment ( 25201988) Height ( 28552196) High density lipoprotein cholesterol levels ( 29403010) Hip circumference adjusted for BMI ( 34021172) Lymphocyte count ( 27863252) Schizophrenia ( 25056061 29483656 23974872) Tourette syndrome ( 30818990) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 26426971 34021172) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	A body shape index ( 34021172) Adiponectin levels ( 22479202 31178129) Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) Appendicular lean mass ( 33097823) Atrial fibrillation ( 29892015) Coronary artery disease ( 29212778) Fasting insulin ( 34059833) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference adjusted for BMI ( 34021172 28552196) Hip index ( 34021172) Low density lipoprotein cholesterol levels ( 32154731) Lymphocyte count ( 32888494 27863252) Osteoarthritis (hip) ( 23989986) Reticulocyte count ( 27863252 32888494) Reticulocyte fraction of red cells ( 32888494) Visceral adipose tissue adjusted for BMI ( 22589738) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 25673412 28448500 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 30389748 26426971 34021172) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 28448500) White blood cell count ( 32888494)
Interacting Genes		2 interacting genes: HEXD TUBB3	1 interacting genes: LINC00839
Entrez ID		196383	196385
HPRD ID		10084	13473
Ensembl ID		ENSG00000150977	ENSG00000197653
Uniprot IDs		Q969X0	A0A669KB38 B0I1S1 Q8IVF4
PDB IDs		6RIR 6SQ2 7LWB	8J07
Enriched GO Terms of Interacting Partners?		Netrin Receptor Binding Dorsal Root Ganglion Development Beta-N-acetylhexosaminidase Activity Hexosaminidase Activity Microtubule Netrin-activated Signaling Pathway Ganglion Development Minus-end-directed Microtubule Motor Activity Axonemal Dynein Complex Peptide Binding Microtubule-based Process 9+2 Motile Cilium Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding Dynein Complex Hydrolase Activity, Hydrolyzing O-glycosyl Compounds Microtubule Motor Activity	Protein Transport From Ciliary Membrane To Plasma Membrane Glutaminyl-tRNAGln Biosynthesis Via Transamidation Glutaminyl-tRNA Synthase (glutamine-hydrolyzing) Activity Carbon-nitrogen Ligase Activity, With Glutamine As Amido-N-donor Glutamyl-tRNA(Gln) Amidotransferase Complex
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