ABCA13 and PKD1L1

		ABCA13	PKD1L1
Description		ATP binding cassette subfamily A member 13	polycystin 1 like 1, transient receptor potential channel interacting
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Cytoplasmic Vesicle Membrane Secretory Granule Membrane Cytoplasmic Vesicle Azurophil Granule Membrane Intracellular Membrane-bounded Organelle Intracellular Vesicle	Plasma Membrane Cilium Membrane Calcium Channel Complex Cell Projection Ciliary Membrane Non-motile Cilium
	Molecular Function	Nucleotide Binding Lipid Transporter Activity ATP Binding ATP Hydrolysis Activity ATPase-coupled Transmembrane Transporter Activity ABC-type Transporter Activity	Calcium Channel Activity Protein Binding
	Biological Process	Lipid Transport Positive Regulation Of Cholesterol Transport Ceramide Transport Transmembrane Transport Positive Regulation Of Synaptic Vesicle Endocytosis	Detection Of Nodal Flow Monoatomic Ion Transport Calcium Ion Transport Monoatomic Ion Transmembrane Transport Detection Of Mechanical Stimulus Calcium Ion Transmembrane Transport Left/right Axis Specification Cell-cell Adhesion
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS		Cerebrospinal fluid clusterin levels ( 26545630) DHEAS levels ( 34748635) Gut microbiota (bacterial taxa) ( 27723756) QT interval (ambient particulate matter interaction) ( 28749367) Refractive astigmatism ( 25367360) Vein graft stenosis in coronary artery bypass grafting ( 25881214)	Anxiety disorder ( 25390645) Diastolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415) Gut microbiota alpha diversity (Shannon index) ( 33208821) Hepatitis C induced liver fibrosis ( 22841784) Obstructive sleep apnea during REM sleep (apnea hypopnea index) ( 29077507) Refractive error ( 32231278) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes		3 interacting genes: APOA1 APOA2 CLK1	1 interacting genes: CLK1
Entrez ID		154664	168507
HPRD ID		07422	10154
Ensembl ID		ENSG00000179869	ENSG00000158683
Uniprot IDs		Q86UQ4	Q8TDX9
PDB IDs
Enriched GO Terms of Interacting Partners?		Peptidyl-methionine Modification High-density Lipoprotein Particle Receptor Binding Apolipoprotein Receptor Binding Phosphatidylcholine-sterol O-acyltransferase Activator Activity Protein Oxidation Negative Regulation Of Very-low-density Lipoprotein Particle Remodeling Regulation Of Intestinal Cholesterol Absorption High-density Lipoprotein Particle Clearance Spherical High-density Lipoprotein Particle High-density Lipoprotein Particle Assembly Regulation Of Intestinal Lipid Absorption High-density Lipoprotein Particle Binding Chylomicron Phospholipid Efflux Regulation Of Intestinal Absorption Reverse Cholesterol Transport Very-low-density Lipoprotein Particle High-density Lipoprotein Particle Remodeling High-density Lipoprotein Particle Lipid Transporter Activity Cholesterol Transfer Activity Plasma Lipoprotein Particle Assembly Phosphatidylcholine Biosynthetic Process Protein-lipid Complex Assembly Plasma Lipoprotein Particle Clearance Cholesterol Efflux Lipoprotein Metabolic Process Negative Regulation Of Cytokine Production Involved In Immune Response Plasma Lipoprotein Particle Remodeling Cellular Response To Lipoprotein Particle Stimulus Protein-containing Complex Remodeling Cholesterol Binding Cellular Response To Amyloid-beta Phosphatidylcholine Metabolic Process Heat Shock Protein Binding Regulation Of Cholesterol Transport Response To Amyloid-beta Cholesterol Transport Positive Regulation Of Phagocytosis Sterol Transport Phospholipid Transport Cholesterol Homeostasis Sterol Homeostasis Regulation Of Phagocytosis Cholesterol Metabolic Process Phospholipid Binding Blood Microparticle Sterol Metabolic Process Regulation Of Cytokine Production Involved In Immune Response Receptor Ligand Activity	Alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase Activity G-protein Beta/gamma-subunit Complex ATPase-coupled Transmembrane Transporter Activity Icosanoid Transmembrane Transporter Activity ABC-type Transporter Activity Glucuronoside Transmembrane Transporter Activity Glucuronoside Transport Ciliary Basal Body
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