LINC00052 and SEC11A

		LINC00052	SEC11A
Description		long intergenic non-protein coding RNA 52	SEC11 homolog A, signal peptidase complex subunit
Image		No pdb structure
GO Annotations	Cellular Component	Membrane	Endoplasmic Reticulum Signal Peptidase Complex Endoplasmic Reticulum Membrane Membrane
	Molecular Function		Serine-type Endopeptidase Activity Protein Binding Peptidase Activity Hydrolase Activity
	Biological Process		Signal Peptide Processing Proteolysis Response To Virus
Pathways			SRP-dependent cotranslational protein targeting to membrane Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) Synthesis, secretion, and deacylation of Ghrelin Regulation of CDH1 posttranslational processing and trafficking to plasma membrane Maturation of hRSV A proteins
Drugs
Diseases
GWAS		Logical memory (delayed recall) in normal cognition ( 29274321) Psychosis (methamphetamine induced) ( 23594818) Triglyceride levels in HIV infection ( 33109212)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Hip circumference adjusted for BMI ( 34021172) Response to ketamine in bipolar disorder or major depression (antidepressant effects) ( 30552317) Schizophrenia ( 29483656)
Interacting Genes			5 interacting genes: ADAM33 BCHE CSNK2B NUPR1 SLC35F6
Entrez ID		145978	23478
HPRD ID		08101	07503
Ensembl ID		ENSG00000259527	ENSG00000140612
Uniprot IDs			H0YKT4 P67812
PDB IDs			7P2P
Enriched GO Terms of Interacting Partners?		PH Domain Binding Signal Peptide Processing Signal Peptidase Complex Insulin Receptor Substrate Binding
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