PUSL1 and CALML6

		PUSL1	CALML6
Description		pseudouridine synthase like 1	calmodulin like 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion	Nucleus Cytoplasm
	Molecular Function	RNA Binding Pseudouridine Synthase Activity Isomerase Activity TRNA Pseudouridine Synthase Activity	Calcium Ion Binding Protein Binding Enzyme Regulator Activity Metal Ion Binding
	Biological Process	Pseudouridine Synthesis TRNA Processing RNA Modification TRNA Pseudouridine Synthesis	Microtubule Cytoskeleton Organization
Pathways
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908)	Body mass index ( 26426971)
Interacting Genes		2 interacting genes: APP FBXO7	2 interacting genes: MAP3K7 PCP4
Entrez ID		126789	163688
HPRD ID		08301	12997
Ensembl ID		ENSG00000169972	ENSG00000169885
Uniprot IDs		Q8N0Z8	B1AKR1 Q8TD86
PDB IDs
Enriched GO Terms of Interacting Partners?		Ubiquitin Ligase Complex Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of Catabolic Process Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Notch Signaling Pathway Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Lewy Body Core Protein Ubiquitination Protein Modification By Small Protein Conjugation Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Regulation Of Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Post-translational Protein Modification Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Regulation Of Neuron Apoptotic Process Cellular Response To Manganese Ion Ubiquitin-protein Transferase Activity	Regulation Of CAMKK-AMPK Signaling Cascade Positive Regulation Of CAMKK-AMPK Signaling Cascade I-kappaB Phosphorylation Interleukin-17A-mediated Signaling Pathway Linear Polyubiquitin Binding MAP Kinase Kinase Kinase Kinase Activity Histone Kinase Activity TRNA Pseudouridine Synthase Activity TRNA Pseudouridine Synthesis MyD88-dependent Toll-like Receptor Signaling Pathway ATAC Complex P38MAPK Cascade Positive Regulation Of Cell Size Type II Transforming Growth Factor Beta Receptor Binding Stimulatory C-type Lectin Receptor Signaling Pathway Positive Regulation Of JUN Kinase Activity MAP Kinase Activity Anoikis Positive Regulation Of CGAS/STING Signaling Pathway Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Vascular Associated Smooth Muscle Cell Migration Stress-activated MAPK Cascade Interleukin-33-mediated Signaling Pathway Protein Serine/threonine Kinase Binding Response To Angiotensin Toll-like Receptor 3 Signaling Pathway Cellular Response To Lectin Cellular Response To Angiotensin MAP Kinase Kinase Kinase Activity Fc-epsilon Receptor Signaling Pathway Stress-activated Protein Kinase Signaling Cascade Pseudouridine Synthesis Pseudouridine Synthase Activity Endolysosomal Toll-like Receptor Signaling Pathway Interleukin-1-mediated Signaling Pathway CGAS/STING Signaling Pathway Positive Regulation Of T Cell Cytokine Production Protein Exit From Endoplasmic Reticulum Non-canonical NF-kappaB Signal Transduction
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