TMEM219 and ZNF785

		TMEM219	ZNF785
Description		transmembrane protein 219	zinc finger protein 785
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Nucleus
	Molecular Function	Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Apoptotic Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways		TP53 Regulates Transcription of Death Receptors and Ligands	Generic Transcription Pathway
Drugs
Diseases
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Anxiety/tension (special factor of neuroticism) ( 30867560) Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Dentures ( 31235808) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Schizophrenia ( 25056061 28991256 29483656) Waist circumference adjusted for body mass index ( 34021172)	Eosinophil count ( 27863252)
Interacting Genes			22 interacting genes: CABP2 CBY2 CCDC136 CCNDBP1 CEP70 EHMT2 GOLGA6L9 HOOK1 KIFC3 KRT36 KRTAP10-1 KRTAP10-5 KRTAP12-2 MDFI MID2 MTUS2 PRR7 RSPH1 STX1A STX2 TPM2 TRIP6
Entrez ID		124446	146540
HPRD ID		18546	08120
Ensembl ID		ENSG00000149932	ENSG00000197162
Uniprot IDs		A0A024R618 Q86XT9	A8K8V0
PDB IDs
Enriched GO Terms of Interacting Partners?		Vesicle Fusion To Plasma Membrane Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Synaptic Vesicle Membrane Organization Negative Regulation Of Short-term Synaptic Potentiation Positive Regulation Of Spontaneous Neurotransmitter Secretion Negative Regulation Of Macropinocytosis Negative Regulation Of Synaptic Vesicle Recycling Vesicle Fusion Negative Regulation Of SNARE Complex Assembly Postsynaptic Density Membrane Organelle Membrane Fusion Regulation Of Calcium-dependent Activation Of Synaptic Vesicle Fusion Methylation-dependent Protein Binding Modulation Of Chemical Synaptic Transmission Negative Regulation Of Vesicle Fusion Organelle Fusion Regulation Of Synaptic Activity Regulation Of Vesicle-mediated Transport Negative Regulation Of Pinocytosis Membrane Fusion Regulation Of Spontaneous Synaptic Transmission Spontaneous Neurotransmitter Secretion SAGA-type Complex Histone H3K36me3 Reader Activity Regulation Of Synaptic Plasticity Calcium Ion-regulated Exocytosis Of Neurotransmitter Establishment Of Protein Localization To Chromatin Neuromuscular Process Controlling Posture Presynapse Nuclear Lamina Synaptic Vesicle Docking Regulation Of Synaptic Vesicle Priming Asymmetric Synapse ATAC Complex Regulation Of Short-term Neuronal Synaptic Plasticity Regulation Of SNARE Complex Assembly	Identical Protein Binding Cytoskeleton Intermediate Filament Microtubule Binding Keratin Filament Spermatid Development Presynaptic Active Zone Membrane Vesicle Organization
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