DNAAF1 and LINC00311

		DNAAF1	LINC00311
Description		dynein axonemal assembly factor 1	long intergenic non-protein coding RNA 311
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Spindle Pole Extracellular Region Cytoplasm Cytoskeleton Cilium Axoneme Cell Projection
	Molecular Function	Dynein Complex Binding
	Biological Process	Heart Looping Cilium Movement Regulation Of Cilium Beat Frequency Lung Development Axoneme Assembly Determination Of Pancreatic Left/right Asymmetry Outer Dynein Arm Assembly Inner Dynein Arm Assembly Motile Cilium Assembly Cilium Assembly Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Left/right Pattern Formation Axonemal Dynein Complex Assembly Determination Of Digestive Tract Left/right Asymmetry Determination Of Liver Left/right Asymmetry
Pathways
Drugs
Diseases		Primary ciliary dyskinesia, including: Primary ciliary dyskinesia; Kartagener syndrome
GWAS		Post bronchodilator FEV1/FVC ratio ( 26634245) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872) Systolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415)	Systolic blood pressure ( 30224653) Triglyceride levels x loop diuretics use interaction ( 31806883)
Interacting Genes			1 interacting genes: CD2
Entrez ID		123872	197196
HPRD ID		14023	14484
Ensembl ID		ENSG00000154099	ENSG00000179219
Uniprot IDs		A0A140VJN4 Q8NEP3
PDB IDs
Enriched GO Terms of Interacting Partners?			Membrane Raft Distribution Membrane Raft Polarization Membrane Raft Localization Positive Regulation Of Myeloid Dendritic Cell Activation Determination Of Pancreatic Left/right Asymmetry Determination Of Liver Left/right Asymmetry Determination Of Digestive Tract Left/right Asymmetry Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Left/right Pattern Formation Inner Dynein Arm Assembly Regulation Of Cilium Beat Frequency Outer Dynein Arm Assembly Dynein Complex Binding Membrane Raft Organization Heterotypic Cell-cell Adhesion Regulation Of Cilium Movement Axonemal Dynein Complex Assembly Natural Killer Cell Mediated Immunity Natural Killer Cell Mediated Cytotoxicity Motile Cilium Assembly Epithelial Cilium Movement Involved In Extracellular Fluid Movement Natural Killer Cell Activation Axoneme Assembly Extracellular Transport Regulation Of Microtubule-based Movement Receptor Tyrosine Kinase Binding Positive Regulation Of Interleukin-8 Production Heart Looping Embryonic Heart Tube Morphogenesis Positive Regulation Of Type II Interferon Production Leukocyte Mediated Cytotoxicity Regulation Of Interleukin-8 Production Determination Of Bilateral Symmetry Microtubule Bundle Formation Determination Of Left/right Symmetry
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