SLC27A3 and KCNN3

		SLC27A3	KCNN3
Description		solute carrier family 27 member 3	potassium calcium-activated channel subfamily N member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Mitochondrial Membrane	Cytoplasm Plasma Membrane Membrane Z Disc Neuron Projection Neuronal Cell Body
	Molecular Function	Nucleotide Binding Long-chain Fatty Acid-CoA Ligase Activity ATP Binding Ligase Activity Very Long-chain Fatty Acid-CoA Ligase Activity Arachidonate-CoA Ligase Activity	Inward Rectifier Potassium Channel Activity Protein Binding Calmodulin Binding Calcium-activated Potassium Channel Activity Small Conductance Calcium-activated Potassium Channel Activity
	Biological Process	Long-chain Fatty Acid Metabolic Process Lipid Metabolic Process Fatty Acid Metabolic Process Lipid Transport Fatty Acid Transport	Monoatomic Ion Transport Potassium Ion Transport Monoatomic Ion Transmembrane Transport Potassium Ion Transmembrane Transport
Pathways		Synthesis of very long-chain fatty acyl-CoAs	Ca2+ activated K+ channels
Drugs			Procaine Ritodrine Nitrendipine Miconazole Colforsin Dequalinium Trimebutine Rimtuzalcap
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Chronotype ( 30696823) Cooked vegetable consumption ( 32066663) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) Height ( 31562340) Neonatal white matter microstructure ( 33009551) Number of children ever born ( 27798627) Raw vegetable consumption ( 32066663) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	A body shape index ( 34021172) Alzheimer's disease in APOE e4- carriers ( 25778476) Atrial fibrillation ( 22544366 20173747 28416818 30061737 29892015 29290336) Bipolar disorder ( 31043756) Birth weight ( 31043758) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Heel bone mineral density x serum urate levels interaction ( 34046847) Height ( 28552196) Incident atrial fibrillation ( 28416818) Interleukin-6 levels ( 33517400) Obesity-related traits ( 23251661) Offspring birth weight ( 31043758) Prevalent atrial fibrillation ( 28416818) Prostate cancer ( 23535732) Squamous cell lung carcinoma ( 28604730) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Waist circumference adjusted for body mass index ( 28552196) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		1 interacting genes: WEE2-AS1	7 interacting genes: APP CALM1 CLCN7 EMD ERMP1 FCER1G NAPB
Entrez ID		11000	3782
HPRD ID		11967	04283
Ensembl ID		ENSG00000143554	ENSG00000143603
Uniprot IDs		Q5K4L6 X6R3N0	A0A087WYJ0 Q9UGI6
PDB IDs
Enriched GO Terms of Interacting Partners?		Calcium-activated Potassium Channel Activity Small Conductance Calcium-activated Potassium Channel Activity Positive Regulation Of Stress Granule Assembly Regulation Of Stress Granule Assembly Pre-mRNA 5'-splice Site Binding MRNA 5'-splice Site Recognition Inward Rectifier Potassium Channel Activity Stress Granule Assembly Binding Of Sperm To Zona Pellucida PcG Protein Complex Hematopoietic Stem Cell Homeostasis MRNA Splice Site Recognition U1 SnRNP Sperm-egg Recognition Cell-cell Recognition
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