PDIA5 and FAM162A

		PDIA5	FAM162A
Description		protein disulfide isomerase family A member 5	family with sequence similarity 162 member A
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane	Mitochondrion Cytosol Membrane Mitochondrial Membrane
	Molecular Function	Protein Disulfide Isomerase Activity Protein Binding Protein-disulfide Reductase Activity Oxidoreductase Activity Isomerase Activity	Protein Binding
	Biological Process	Protein Folding Electron Transport Chain	Apoptotic Process Positive Regulation Of Apoptotic Process Neuron Apoptotic Process Cellular Response To Hypoxia Positive Regulation Of Release Of Cytochrome C From Mitochondria
Pathways		XBP1(S) activates chaperone genes
Drugs
Diseases
GWAS		Fibrinogen levels ( 26561523 28107422) Interleukin-17 levels ( 27989323) Mean platelet volume ( 27863252 32888494) Platelet count ( 22139419 27863252 32888494) Platelet distribution width ( 27863252 32888494) Plateletcrit ( 27863252 32888494)	Diastolic blood pressure ( 27841878) Risky sexual behaviors (alcohol dependence interaction) ( 28990359)
Interacting Genes		6 interacting genes: KRTAP1-3 KRTAP10-3 KRTAP10-7 MDFI OGT UBQLN4	2 interacting genes: HSP90AA1 UBC
Entrez ID		10954	26355
HPRD ID		08334	06422
Ensembl ID		ENSG00000065485	ENSG00000114023
Uniprot IDs		Q14554	Q96A26 Q9H2P1
PDB IDs		4I6X
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly
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