SPINT3 and IFT52

		SPINT3	IFT52
Description		serine peptidase inhibitor, Kunitz type 3	intraflagellar transport 52
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region	Centrosome Centriole Cilium Intraciliary Transport Particle B Motile Cilium Photoreceptor Connecting Cilium Ciliary Basal Body Cell Projection Dendrite Terminus Ciliary Tip Ciliary Base Photoreceptor Cell Cilium
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Peptidase Inhibitor Activity	Protein Binding
	Biological Process		Neural Tube Formation Heart Looping Smoothened Signaling Pathway Determination Of Left/right Symmetry Dorsal/ventral Pattern Formation Negative Regulation Of Keratinocyte Proliferation Cell Projection Organization Intraciliary Anterograde Transport Intraciliary Transport Embryonic Digit Morphogenesis Keratinocyte Proliferation Cilium Assembly Regulation Of Protein Processing Non-motile Cilium Assembly
Pathways			Hedgehog 'off' state Intraflagellar transport Intraflagellar transport
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Brain structure ( 20171287)	Mean reticulocyte volume ( 32888494)
Interacting Genes
Entrez ID		10816	51098
HPRD ID		19468	12789
Ensembl ID		ENSG00000101446	ENSG00000101052
Uniprot IDs		P49223	Q9Y366
PDB IDs
Enriched GO Terms of Interacting Partners?		Photoreceptor Cell Cilium Neural Tube Formation Dendrite Terminus Epithelial Tube Formation Non-motile Cilium Assembly Embryonic Epithelial Tube Formation Embryonic Digit Morphogenesis Ciliary Tip Regulation Of Keratinocyte Proliferation Dorsal/ventral Pattern Formation Negative Regulation Of Keratinocyte Proliferation Regulation Of Protein Processing Intraciliary Transport Particle B Photoreceptor Connecting Cilium Keratinocyte Proliferation Heart Looping Embryonic Heart Tube Morphogenesis Intraciliary Transport Regulation Of Protein Maturation Ciliary Base Intraciliary Anterograde Transport Smoothened Signaling Pathway Determination Of Bilateral Symmetry Determination Of Left/right Symmetry Epithelial Tube Morphogenesis Tube Formation Negative Regulation Of Epithelial Cell Proliferation Centriole Transport Along Microtubule Epithelial Cell Proliferation Cytoskeleton-dependent Intracellular Transport Microtubule-based Transport Motile Cilium Cilium Assembly Regionalization Tube Morphogenesis Cilium Organization Ciliary Basal Body Morphogenesis Of An Epithelium Plasma Membrane Bounded Cell Projection Assembly Regulation Of Epithelial Cell Proliferation Cell Projection Assembly Regulation Of Proteolysis Pattern Specification Process Tissue Morphogenesis Microtubule-based Movement Embryonic Morphogenesis	Serine-type Endopeptidase Inhibitor Activity Protein Targeting To Mitochondrion Establishment Of Protein Localization To Mitochondrion Heat Shock Protein Binding Peptidase Inhibitor Activity
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