PITRM1 and LARP4B

		PITRM1	LARP4B
Description		pitrilysin metallopeptidase 1	La ribonucleoprotein 4B
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Nucleolus Cytoplasm Cytosol Cytoplasmic Stress Granule Membrane
	Molecular Function	Metalloendopeptidase Activity Protein Binding Enzyme Activator Activity Peptidase Activity Metallopeptidase Activity Zinc Ion Binding Hydrolase Activity Metal Ion Binding	Nucleic Acid Binding RNA Binding MRNA 3'-UTR Binding Protein Binding
	Biological Process	Proteolysis Protein Targeting To Mitochondrion Protein Processing	Regulation Of Translation Positive Regulation Of Translation Positive Regulation Of 3'-UTR-mediated MRNA Stabilization
Pathways		Mitochondrial protein import
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder and conduct disorder ( 18951430) Metabolite levels ( 23823483) Scalp hair shape ( 26926045)	Basophil count ( 32888494) Basophil percentage of granulocytes ( 27863252) Basophil percentage of white cells ( 27863252 32888494) Bisphosphonate-associated atypical femoral fracture ( 31006051) Blood urea nitrogen levels ( 31152163) Chronic kidney disease ( 31152163) Chronotype ( 30696823) Estimated glomerular filtration rate ( 31015462 31451708 31152163) Estimated glomerular filtration rate in non-diabetics ( 31451708) Femur bone mineral density x serum urate levels interaction ( 34046847) Neutrophil percentage of granulocytes ( 27863252) Prostate cancer ( 29892016) Prostate cancer (advanced) ( 29892016) Prostate cancer (early onset) ( 29892016) Reticulocyte fraction of red cells ( 32888494) Sum eosinophil basophil counts ( 27863252) White blood cell count (basophil) ( 27863252)
Interacting Genes			7 interacting genes: ATXN1L C1QTNF9 DMRTB1 MAGED1 OGT PABPC1 RBPMS
Entrez ID		10531	23185
HPRD ID		07142	13787
Ensembl ID		ENSG00000107959	ENSG00000107929
Uniprot IDs		A0A0A0MRX9 A0A7I2V397 Q5JRX3	Q92615
PDB IDs		4L3T 4NGE 4RPU 6XOS 6XOT 6XOU 6XOV 6XOW	3PTH
Enriched GO Terms of Interacting Partners?		Protein Targeting To Mitochondrion	Dimethylallyl Diphosphate Biosynthetic Process Isopentenyl-diphosphate Delta-isomerase Activity Intramolecular Oxidoreductase Activity Isopentenyl Diphosphate Biosynthetic Process Isopentenyl Diphosphate Metabolic Process Isoprenoid Biosynthetic Process Cholesterol Biosynthetic Process Sterol Biosynthetic Process Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly
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