RASA4 and ZAN

		RASA4	ZAN
Description		RAS p21 protein activator 4	zonadhesin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Membrane	Extracellular Space Plasma Membrane Membrane Extracellular Matrix
	Molecular Function	GTPase Activator Activity Phospholipid Binding Zinc Ion Binding Metal Ion Binding	Extracellular Matrix Structural Constituent
	Biological Process	Negative Regulation Of GTPase Activity Intracellular Signal Transduction Negative Regulation Of Ras Protein Signal Transduction Cellular Response To Calcium Ion Regulation Of Intracellular Signal Transduction	Cell Adhesion Binding Of Sperm To Zona Pellucida Cell-cell Adhesion
Pathways		Regulation of RAS by GAPs
Drugs
Diseases
GWAS		Chronotype ( 27494321) Morning vs. evening chronotype ( 27494321) Type 2 diabetes ( 32499647)	Bipolar disorder ( 31043756) Heel bone mineral density ( 30598549) Red blood cell count ( 32888494) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 34021172) White matter hyperintensities ( 32358547)
Interacting Genes		5 interacting genes: APMAP ERBB3 HRAS JPT2 OVGP1
Entrez ID		10156	7455
HPRD ID		12135	03846
Ensembl ID		ENSG00000105808	ENSG00000146839
Uniprot IDs		E7ERK1 O43374	B4DYT6 Q9Y493
PDB IDs
Enriched GO Terms of Interacting Partners?		Schwann Cell Development Positive Regulation Of Cardiac Muscle Tissue Development ERBB3:ERBB2 Complex Neuron Apoptotic Process Glial Cell Development Regulation Of Calcium-mediated Signaling Myelination Axon Ensheathment GTPase Complex Perivitelline Space ErbB-3 Class Receptor Binding Neuregulin Receptor Activity Neuregulin Binding Regulation Of Cardiac Muscle Tissue Development Negative Regulation Of Neuron Apoptotic Process Phospholipase C Activator Activity Negative Regulation Of Binding Of Sperm To Zona Pellucida Chitin Metabolic Process Regulation Of Binding Of Sperm To Zona Pellucida Chitin Catabolic Process Chitinase Activity Egg Coat Arylesterase Activity Positive Regulation Of Epithelial Cell Proliferation Schwann Cell Differentiation Oncogene-induced Cell Senescence Chitin Binding ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway Regulation Of Neuron Apoptotic Process T-helper 1 Type Immune Response Negative Regulation Of Motor Neuron Apoptotic Process Endocardial Cushion Development Regulation Of Motor Neuron Apoptotic Process Motor Neuron Apoptotic Process Apoptotic Signaling Pathway Positive Regulation Of Ruffle Assembly Endocytosis Involved In Viral Entry Into Host Cell Protein Tyrosine Kinase Activator Activity
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