SLC17A4 and FAM8A1

		SLC17A4	FAM8A1
Description		solute carrier family 17 member 4	family with sequence similarity 8 member A1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Apical Plasma Membrane Brush Border Membrane	Hrd1p Ubiquitin Ligase Complex Membrane
	Molecular Function	Sodium:phosphate Symporter Activity Urate Transmembrane Transporter Activity Symporter Activity Thyroid Hormone Transmembrane Transporter Activity Transmembrane Transporter Activity	Protein Binding
	Biological Process	Phosphate-containing Compound Metabolic Process Monoatomic Ion Transport Sodium Ion Transport Urate Transport Sodium Ion Transmembrane Transport Sodium-dependent Phosphate Transport Transmembrane Transport Thyroid Hormone Transport	ERAD Pathway
Pathways
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Cardiovascular disease risk factors ( 21943158) Carotid intima media thickness ( 21909108) Feeling guilty ( 29500382) Fish- and plant-related diet ( 32066663) Free thyroxine concentration ( 30367059) Gout ( 31578528) Hemoglobin levels ( 32327693) Intelligence (MTAG) ( 29326435) Lung cancer ( 28604730) Neurofibrillary tangles ( 25188341) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Refractive error ( 32231278) Schizophrenia ( 30285260) Subcortical volume (MOSTest) ( 32665545) Systemic lupus erythematosus ( 28714469) Urate levels ( 31578528) Urate levels in lean individuals ( 25811787) Urate levels in overweight individuals ( 25811787) Urinary metabolite levels in chronic kidney disease ( 31959995) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995)	Idiopathic intracranial hypertension ( 29608535)
Interacting Genes			1 interacting genes: ATP13A2
Entrez ID		10050	51439
HPRD ID		05022	13316
Ensembl ID		ENSG00000146039	ENSG00000137414
Uniprot IDs		Q9Y2C5	Q9UBU6
PDB IDs
Enriched GO Terms of Interacting Partners?		Hrd1p Ubiquitin Ligase Complex	GMP Reductase Activity GMP Reductase Complex Polyamine Transmembrane Transporter Activity Extracellular Exosome Biogenesis Spermine Transmembrane Transport ABC-type Polyamine Transporter Activity Extracellular Vesicle Biogenesis Spermine Transport P-type Ion Transporter Activity Negative Regulation Of Lysosomal Protein Catabolic Process P-type Transmembrane Transporter Activity Regulation Of Autophagosome Size Cupric Ion Binding Negative Regulation Of Interleukin-4 Production Urate Transport Urate Transmembrane Transporter Activity Thyroid Hormone Transmembrane Transporter Activity Sodium-dependent Phosphate Transport Regulation Of Chaperone-mediated Autophagy Polyamine Transmembrane Transport Cellular Response To Manganese Ion Sodium:phosphate Symporter Activity Thyroid Hormone Transport ATPase-coupled Monoatomic Cation Transmembrane Transporter Activity Regulation Of Lysosomal Protein Catabolic Process Response To Manganese Ion Autophagosome-lysosome Fusion Positive Regulation Of Exosomal Secretion
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