SCO2

Description		synthesis of cytochrome C oxidase 2
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane Myofibril
	Molecular Function	Copper Ion Binding Protein Binding Protein-disulfide Reductase Activity Copper Chaperone Activity Metal Ion Binding
	Biological Process	Eye Development In Utero Embryonic Development Muscle System Process Intracellular Copper Ion Homeostasis Respiratory Chain Complex IV Assembly Response To Activity Respiratory Electron Transport Chain Mitochondrial Cytochrome C Oxidase Assembly Copper Ion Homeostasis
Pathways		TP53 Regulates Metabolic Genes Complex IV assembly
Drugs
Diseases
GWAS		Chronic lymphocytic leukemia ( 28165464) Granulocyte percentage of myeloid white cells ( 27863252) Mean corpuscular hemoglobin ( 20139978 32888494) Mean corpuscular volume ( 32888494) Multiple sclerosis ( 21833088) Red blood cell traits ( 23222517) Red cell distribution width ( 32888494) Serum metabolite levels ( 33031748)
Interacting Genes		2 interacting genes: APP CIDEB
Entrez ID		9997
HPRD ID		05042
Ensembl ID		ENSG00000284194
Uniprot IDs		O43819
PDB IDs		2RLI
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Lipid Droplet Fusion Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Positive Regulation Of Apoptotic Process Peptidase Activator Activity Positive Regulation Of Programmed Cell Death Cellular Response To Manganese Ion Apoptotic Process Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding Golgi-associated Vesicle Insulin Receptor Binding Apolipoprotein Binding Response To Lead Ion Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel
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