FGF19

Gene Name		fibroblast growth factor 19
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Gene Ontology Annotations	Cellular Component	Extracellular Region
	Molecular Function	Fibroblast Growth Factor Receptor Binding Protein Binding Growth Factor Activity
	Biological Process	Neural Crest Cell Migration Positive Regulation Of Protein Phosphorylation Epidermal Growth Factor Receptor Signaling Pathway Nervous System Development Heart Development Positive Regulation Of Cell Proliferation Insulin Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of Gene Expression Fc-epsilon Receptor Signaling Pathway Innate Immune Response Positive Regulation Of Glucose Import Positive Regulation Of JNK Cascade Neurotrophin TRK Receptor Signaling Pathway Phosphatidylinositol-mediated Signaling Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Bile Acid Biosynthetic Process
Pathways		Signaling by the B Cell Receptor (BCR) Phospholipase C-mediated cascade Signaling by FGFR in disease SHC-mediated cascade Signaling by EGFRvIII in Cancer Signaling by SCF-KIT DAP12 signaling Downstream signaling events of B Cell Receptor (BCR) PI3K/AKT activation PI-3K cascade PI3K Cascade Negative regulation of FGFR signaling Signaling by PDGF DAP12 interactions GAB1 signalosome Signaling by ERBB4 Role of LAT2/NTAL/LAB on calcium mobilization Constitutive PI3K/AKT Signaling in Cancer PI3K events in ERBB4 signaling Signaling by ERBB2 FGFR4 ligand binding and activation Signaling by EGFR Downstream signal transduction Fc epsilon receptor (FCERI) signaling Signaling by EGFR in Cancer PI3K/AKT Signaling in Cancer Adaptive Immune System IRS-mediated signalling PIP3 activates AKT signaling IGF1R signaling cascade IRS-related events triggered by IGF1R PI3K events in ERBB2 signaling Downstream signaling of activated FGFR FGFR ligand binding and activation Signaling by Insulin receptor Innate Immune System Signalling by NGF Insulin receptor signalling cascade IRS-related events Signaling by Ligand-Responsive EGFR Variants in Cancer NGF signalling via TRKA from the plasma membrane Signaling by Overexpressed Wild-Type EGFR in Cancer betaKlotho-mediated ligand binding Signaling by FGFR Klotho-mediated ligand binding FRS2-mediated cascade IRS-mediated signalling Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) PI3K Cascade
Drugs
Diseases
GWAS		Breast cancer ( 20453838)
Protein-protein Interactions		1 interactors: FGFR4
Entrez ID		9965
HPRD ID		04868
Ensembl ID		ENSG00000162344
Uniprot IDs		O95750
PDB IDs		1PWA 2P23
Enriched GO Terms of Interacting Partners?		Alveolar Secondary Septum Development Positive Regulation Of Metalloenzyme Activity Regulation Of Bile Acid Biosynthetic Process Phosphate Ion Homeostasis Lung Saccule Development Regulation Of Cholesterol Homeostasis Positive Regulation Of DNA Biosynthetic Process Regulation Of Extracellular Matrix Disassembly Organ Induction Regulation Of Extracellular Matrix Organization Anion Homeostasis Regulation Of DNA Biosynthetic Process Developmental Induction Regulation Of Organ Formation Lung Alveolus Development Lung Epithelium Development Regulation Of Steroid Biosynthetic Process Regulation Of Steroid Metabolic Process Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of Lipid Biosynthetic Process Phosphatidylinositol-mediated Signaling Positive Regulation Of DNA Metabolic Process Insulin Receptor Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Organ Morphogenesis Cellular Response To Fibroblast Growth Factor Stimulus Regulation Of ERK1 And ERK2 Cascade Response To Fibroblast Growth Factor Glucose Homeostasis Protein Autophosphorylation Neurotrophin TRK Receptor Signaling Pathway Cellular Response To Insulin Stimulus Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway Lung Development Respiratory Tube Development Fc Receptor Signaling Pathway Peptidyl-tyrosine Phosphorylation Respiratory System Development Cell Fate Commitment Response To Insulin Regulation Of Lipid Metabolic Process Positive Regulation Of Proteolysis Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Immune Response-regulating Cell Surface Receptor Signaling Pathway
Tagcloud ?		aberrantly af anr atrial autonomic bioinformatics canine copyright dysregulated fgf3 fgf4 fibrillation filtering inducibility lentiviruses lncrnas nearby neurogenesis orchestrators pads pipelines prolong reserved rights shorten slc25a4 tcons transcriptomes twofold