HS3ST4

Description		heparan sulfate-glucosamine 3-sulfotransferase 4
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane
	Molecular Function	Sulfotransferase Activity [heparan Sulfate]-glucosamine 3-sulfotransferase Activity Transferase Activity
	Biological Process	Heparan Sulfate Proteoglycan Biosynthetic Process Heparan Sulfate Proteoglycan Metabolic Process
Pathways		HS-GAG biosynthesis
Drugs
Diseases
GWAS		Dental caries (decayed, missing and filled tooth surfaces) ( 31533690) Disease progression in age-related macular degeneration ( 29346644) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Gut microbiota relative abundance (Faecalibacterium) ( 33208821) Lack of perseverance ( 30718321) Nose morphology ( 29921221) Obesity-related traits ( 23251661) Obstructive sleep apnea trait (apnea hypopnea index) ( 29077507) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Pallidum volume ( 31530798) PEG-asparaginase hypersensitivity without enzyme activity in childhood acute lymphoblastic leukaemia ( 30450575) Vaginal microbiome composition (Shannon diversity index) ( 32723796) Verbal declarative memory ( 25648963)
Novel Interacting Genes		1 novel interacting genes: DOC2A
Interacting Genes
Entrez ID		9951
HPRD ID		04960
Ensembl ID		ENSG00000182601
Uniprot IDs		Q9Y661
PDB IDs
Enriched GO Terms of Interacting Partners?		Spontaneous Neurotransmitter Secretion Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Positive Regulation Of Calcium Ion-dependent Exocytosis Calcium-dependent Activation Of Synaptic Vesicle Fusion Positive Regulation Of Vesicle Fusion Extrinsic Component Of Synaptic Vesicle Membrane Regulation Of Calcium Ion-dependent Exocytosis Synaptic Vesicle Exocytosis Regulation Of Vesicle Fusion Neurotransmitter Secretion Positive Regulation Of Regulated Secretory Pathway Calcium-dependent Phospholipid Binding Positive Regulation Of Exocytosis Vesicle-mediated Transport In Synapse Neurotransmitter Transport Regulated Exocytosis Regulation Of Regulated Secretory Pathway Synaptic Vesicle Membrane Signal Release Regulation Of Exocytosis Exocytosis Positive Regulation Of Secretion By Cell Trans-synaptic Signaling Positive Regulation Of Secretion Neuron Projection Synaptic Signaling Chemical Synaptic Transmission
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