GFPT2

Description		glutamine--fructose-6-phosphate transaminase 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol
	Molecular Function	Glutamine-fructose-6-phosphate Transaminase (isomerizing) Activity Protein Binding Transaminase Activity Transferase Activity Carbohydrate Derivative Binding
	Biological Process	Fructose 6-phosphate Metabolic Process UDP-N-acetylglucosamine Metabolic Process UDP-N-acetylglucosamine Biosynthetic Process Energy Reserve Metabolic Process Protein N-linked Glycosylation Carbohydrate Derivative Metabolic Process Carbohydrate Derivative Biosynthetic Process Cellular Response To Leukemia Inhibitory Factor
Pathways		Synthesis of UDP-N-acetyl-glucosamine
Drugs
Diseases
GWAS		Fat distribution (HIV) ( 21897333) Femur bone mineral density x serum urate levels interaction ( 34046847) Height ( 20881960) Hip circumference adjusted for BMI ( 34021172) Subclinical trait of interstitial lung disease (basilar peel-core ratio of high attentuation areas on CT scan) ( 28521775)
Novel Interacting Genes		1 novel interacting genes: TENM2
Interacting Genes		4 interacting genes: CLIC6 MTNR1A POT1 UBC
Entrez ID		9945
HPRD ID		04842
Ensembl ID		ENSG00000131459
Uniprot IDs		A0A0S2Z4X9 B3KMR8 O94808
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding D4 Dopamine Receptor Binding Melatonin Receptor Activity Positive Regulation Of Telomeric Loop Disassembly 8-hydroxy-2'-deoxyguanosine DNA Binding Telomeric G-quadruplex DNA Binding Telomeric D-loop Binding Telomere Assembly D2 Dopamine Receptor Binding D3 Dopamine Receptor Binding Retrograde Trans-synaptic Signaling By Trans-synaptic Protein Complex Single-stranded Telomeric DNA Binding Telomerase Inhibitor Activity Shelterin Complex Establishment Of Protein Localization To Telomere Trans-synaptic Signaling By Trans-synaptic Complex DEAD/H-box RNA Helicase Binding Nuclear Telomere Cap Complex Telomeric D-loop Disassembly G-rich Strand Telomeric DNA Binding Telomeric Loop Disassembly Telomere Capping Hormone Binding Protein Tag Activity Regulation Of DNA Strand Elongation Mating Behavior Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Maintenance Via Telomerase Positive Regulation Of Telomere Maintenance Via Telomerase RNA-templated DNA Biosynthetic Process Telomere Maintenance Via Telomere Lengthening Telomeric DNA Binding Regulation Of Double-strand Break Repair Via Nonhomologous End Joining Positive Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Filopodium Assembly
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