IQSEC1

Gene Name		IQ motif and Sec7 domain 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Trans-Golgi Network Membrane
	Molecular Function	ARF Guanyl-nucleotide Exchange Factor Activity
	Biological Process	Vesicle-mediated Transport Actin Cytoskeleton Organization Regulation Of ARF Protein Signal Transduction Positive Regulation Of GTPase Activity
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		1 interactors: APOE
Entrez ID		9922
HPRD ID		11052
Ensembl ID		ENSG00000144711
Uniprot IDs		B4DGC5 Q6DN90
PDB IDs		3QWM 4C0A
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Positive Regulation Of Dendritic Spine Maintenance Negative Regulation Of Dendritic Spine Maintenance Negative Regulation Of Phospholipid Efflux Negative Regulation Of Lipid Transport Across Blood Brain Barrier Positive Regulation Of Lipid Transport Across Blood Brain Barrier Positive Regulation Of Postsynaptic Membrane Organization Negative Regulation Of Postsynaptic Membrane Organization Positive Regulation Of Neurofibrillary Tangle Assembly Negative Regulation Of Presynaptic Membrane Organization Positive Regulation Of Presynaptic Membrane Organization Positive Regulation Of Phospholipid Efflux Negative Regulation Of Cholesterol Biosynthetic Process Regulation Of Postsynaptic Membrane Organization Very-low-density Lipoprotein Particle Clearance Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Negative Regulation Of Cholesterol Efflux N-methyl-D-aspartate Receptor Clustering Regulation Of Tau-protein Kinase Activity Regulation Of Presynaptic Membrane Organization Negative Regulation Of Dendritic Spine Development High-density Lipoprotein Particle Clearance Positive Regulation Of Inclusion Body Assembly Regulation Of Beta-amyloid Clearance Very-low-density Lipoprotein Particle Remodeling Positive Regulation Of Cholesterol Esterification Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering High-density Lipoprotein Particle Assembly Positive Regulation Of Phospholipid Transport Chylomicron Remnant Clearance Regulation Of Cholesterol Esterification Peripheral Nervous System Axon Regeneration Triglyceride-rich Lipoprotein Particle Remodeling Negative Regulation Of Beta-amyloid Formation CGMP-mediated Signaling Low-density Lipoprotein Particle Remodeling Cholesterol Catabolic Process Negative Regulation Of Cholesterol Transport Phospholipid Efflux Synaptic Transmission, Cholinergic Positive Regulation Of Beta-amyloid Formation Positive Regulation Of Membrane Protein Ectodomain Proteolysis Cellular Response To Cholesterol Negative Regulation Of Amyloid Precursor Protein Catabolic Process Fatty Acid Homeostasis Lipoprotein Catabolic Process Negative Regulation Of Dendrite Development Response To Dietary Excess Cellular Response To Sterol Nitric Oxide Mediated Signal Transduction
Tagcloud ?		5e 8e beadchip carbohydrate ckd clu cpg cric determining epigenetically filtration glomerular humanmethylation hypermethylated infinium ingenuity insufficiency islands kidney methylated networks nfkbib nfkbil2 nos3 nphp4 slope tcf3 tgfb3 tgfbi