OSBPL2

Description		oxysterol binding protein like 2
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GO Annotations	Cellular Component	Cytoplasm Lipid Droplet Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Membrane Perinuclear Endoplasmic Reticulum Presynaptic Active Zone Cytoplasmic Component Glutamatergic Synapse
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Lipid Binding Phosphatidylinositol Transfer Activity Cholesterol Binding Sterol Transfer Activity Cholesterol Transfer Activity
	Biological Process	Bile Acid Biosynthetic Process Lipid Transport Plasma Membrane Organization Regulation Of Synaptic Vesicle Priming Phospholipid Transport Cholesterol Transport Intracellular Cholesterol Transport Protein Homotetramerization Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Intermembrane Lipid Transfer
Pathways		Synthesis of bile acids and bile salts
Drugs
Diseases
GWAS		Bipolar disorder ( 34002096) Estimated glomerular filtration rate ( 31152163) Femoral neck bone mineral density ( 29499414) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Lumbar spine bone mineral density ( 29499414) Nicotine dependence symptom count ( 25555482) Prostate cancer ( 23535732) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		4 interacting genes: SNAP25 SNRPF UBC VAPB
Entrez ID		9885
HPRD ID		09473
Ensembl ID		ENSG00000130703
Uniprot IDs		A0A2R8YDU7 B4DKJ8 E7ET92 Q9H1P3
PDB IDs		5ZM8
Enriched GO Terms of Interacting Partners?		Membrane Docking Organelle Localization By Membrane Tethering Vesicle Organization Ribbon Synapse Vesicle Dense Core Granule Exocytosis Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Calcium Ion-regulated Exocytosis Of Neurotransmitter Vesicle Fusion To Plasma Membrane Presynaptic Dense Core Vesicle Exocytosis Neuronal Dense Core Vesicle Exocytosis U4 SnRNP U7 SnRNP PICln-Sm Protein Complex 7-methylguanosine Cap Hypermethylation Endoplasmic Reticulum Localization FFAT Motif Binding Host-mediated Activation Of Viral Genome Replication COPII-coated Vesicle Budding Negative Regulation By Virus Of Viral Protein Levels In Host Cell IRE1-mediated Unfolded Protein Response Endoplasmic Reticulum-plasma Membrane Tethering Host-mediated Perturbation Of Viral Genome Replication Host-mediated Perturbation Of Viral RNA Genome Replication Synaptic Vesicle Docking Somatodendritic Compartment Synaptic Vesicle Membrane Organization BLOC-1 Complex Synaptic Vesicle Priming SMN-Sm Protein Complex Small Nuclear Ribonucleoprotein Complex Methylosome Protein Tag Activity Suppression Of Viral Release By Host Endoplasmic Reticulum Membrane Organization Host-mediated Suppression Of Viral Genome Replication Organelle Localization Syntaxin-1 Binding U1 SnRNP Secretory Granule Localization U5 SnRNP U2-type Prespliceosome Assembly U12-type Spliceosomal Complex Glutamatergic Synapse Neurotransmitter Uptake U2-type Spliceosomal Complex U2-type Catalytic Step 2 Spliceosome U2 SnRNP Viral Release From Host Cell
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