TATDN2

Gene Name		TatD DNase domain containing 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Intracellular Organelle
	Molecular Function	Deoxyribonuclease Activity Endodeoxyribonuclease Activity, Producing 5'-phosphomonoesters Metal Ion Binding
	Biological Process	DNA Catabolic Process, Endonucleolytic DNA Catabolic Process Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Endoplasmic Reticulum Unfolded Protein Response Cellular Protein Metabolic Process
Pathways		IRE1alpha activates chaperones XBP1(S) activates chaperone genes Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS
Protein-protein Interactions		1 interactors: BRCA1
Entrez ID		9797
HPRD ID		18712
Ensembl ID		ENSG00000157014
Uniprot IDs		Q93075
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Positive Regulation Of Histone H3-K9 Acetylation Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Cellular Response To Indole-3-methanol Negative Regulation Of Centriole Replication Dosage Compensation By Inactivation Of X Chromosome Protein K6-linked Ubiquitination Regulation Of Histone H3-K9 Acetylation Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Histone H3-K9 Methylation Dosage Compensation Regulation Of Centriole Replication Positive Regulation Of Histone H3-K4 Methylation Regulation Of Histone H4 Acetylation DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Negative Regulation Of Fatty Acid Biosynthetic Process DNA Damage Response, Signal Transduction Resulting In Transcription Negative Regulation Of Histone Methylation Negative Regulation Of Centrosome Duplication Regulation Of DNA Methylation Negative Regulation Of Histone Acetylation Positive Regulation Of Histone Acetylation Negative Regulation Of Peptidyl-lysine Acetylation Regulation Of Histone H3-K4 Methylation Negative Regulation Of Protein Acetylation Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Protein Acetylation Postreplication Repair Regulation Of Transcription From RNA Polymerase III Promoter Negative Regulation Of Fatty Acid Metabolic Process Regulation Of Gene Expression By Genetic Imprinting Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Genetic Imprinting Regulation Of Fatty Acid Biosynthetic Process Positive Regulation Vascular Endothelial Growth Factor Production G2 DNA Damage Checkpoint Positive Regulation Of Histone Methylation Positive Regulation Of DNA Repair Androgen Receptor Signaling Pathway Regulation Of Centrosome Duplication Protein Autoubiquitination Regulation Of Histone Acetylation Negative Regulation Of Lipid Biosynthetic Process Negative Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Centrosome Cycle Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Histone Methylation
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