TOX

Name	thymocyte selection associated high mobility group box
Structure	No pdb structure
Interactors	6 interactors: BANP DMRTB1 GRAP KRTAP12-1 KRTAP26-1 ZDHHC17
GO Annotations	Cellular Component	Nucleus
	Molecular Function	DNA Binding Protein Binding Chromatin DNA Binding
	Biological Process	Natural Killer Cell Differentiation CD4-positive, CD25-positive, Alpha-beta Regulatory T Cell Lineage Commitment NK T Cell Lineage Commitment Leukocyte Differentiation Chromatin Organization Regulation Of Transcription By RNA Polymerase II Nervous System Development Positive Regulation Of Neuron Projection Development Cerebral Cortex Neuron Differentiation Lymphocyte Differentiation Positive Regulation Of Natural Killer Cell Differentiation CD4-positive, Alpha-beta T Cell Lineage Commitment CD8-positive, Alpha-beta T Cell Lineage Commitment Positive Regulation Of Transcription By RNA Polymerase II Lymph Node Development Peyer's Patch Development Regulation Of Positive Thymic T Cell Selection Positive Regulation Of Neural Precursor Cell Proliferation
GWAS	Chronotype ( 30696823 ) Cognitive performance ( 19734545 ) Height ( 31562340 ) High myopia ( 31816047 ) Hyperopia ( 25233373 ) Mercury levels ( 26025379 ) Modified Stumvoll Insulin Sensitivity Index (BMI interaction) ( 27416945 ) Myopia ( 27182965 25233373 ) Oily fish consumption ( 32066663 ) Parental longevity (father's attained age) ( 29227965 ) Pork consumption ( 32066663 ) Psychological resilience (outcome-based) ( 31081985 ) Refractive astigmatism ( 25367360 ) Refractive error ( 32231278 23396134 ) Risk-taking tendency (4-domain principal component model) ( 30643258 ) Smoking initiation ( 33082346 30617275 ) Smoking initiation (ever regular vs never regular) ( 30679032 ) Smoking status (ever vs never smokers) ( 30643258 ) Spherical equivalent (joint analysis main effects and education interaction) ( 27020472 ) Superior temporal sulcus banks volume ( 31530798 ) Systolic blood pressure ( 30224653 ) Type 1 diabetes ( 34012112 ) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738 )
Entrez ID	9760
HPRD ID	12113
Ensembl ID	ENSG00000198846
Uniprot IDs	O94900
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Postsynaptic Golgi Apparatus Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission Perforant Pathway To Dendrate Granule Cell Synapse Keratin Filament Intermediate Filament Protein-cysteine S-myristoyltransferase Activity Protein-cysteine S-stearoyltransferase Activity