ZNF536

Description		zinc finger protein 536
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Zinc Ion Binding Retinoic Acid-responsive Element Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Negative Regulation Of Neuron Differentiation Negative Regulation Of Retinoic Acid Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs) ( 23648065) Age-related hearing impairment ( 24939585) Atorvastatin-induced myopathy ( 31220337) Body mass index ( 25673413 28892062) Body size at age 10 ( 32376654) Cerebrospinal P-tau181p levels ( 28247064) Chin dimples ( 27182965) Chronotype ( 30696823) Falling risk ( 32999390) General risk tolerance (MTAG) ( 30643258) High density lipoprotein cholesterol levels ( 34074324) Major depressive disorder ( 27479909) Myocardial infarction in hypertension (calcium channel blocker interaction) ( 26516778) Myopia (pathological) ( 23049088) Obesity-related traits ( 23251661) Remission after SSRI treatment in major depression ( 30034349) Schizophrenia ( 29483656 30285260 28991256 25056061) Select biomarker traits ( 17903293) Severe malaria ( 29381699) Severe malaria (adjusted for sickle cell variant rs334) ( 29381699) Waist circumference adjusted for body mass index ( 34021172) Waist-to-hip ratio adjusted for body mass index ( 27195708)
Novel Interacting Genes		3 novel interacting genes: C19orf12 POLR2I TSHZ3
Interacting Genes		1 interacting genes: GGA2
Entrez ID		9745
HPRD ID		15825
Ensembl ID		ENSG00000198597
Uniprot IDs		A0A994J7Z0 K7EQN6 O15090
PDB IDs
Enriched GO Terms of Interacting Partners?		Maintenance Of Transcriptional Fidelity During Transcription Elongation By RNA Polymerase II
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