ZNF536

Name	zinc finger protein 536
Structure	No pdb structure
Novel Interactors	3 novel interactors: C19orf12 POLR2I TSHZ3
Interactors	1 interactors: GGA2
GO Annotations	Cellular Component	Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Zinc Ion Binding Retinoic Acid-responsive Element Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Negative Regulation Of Neuron Differentiation Negative Regulation Of Retinoic Acid Receptor Signaling Pathway
GWAS	Adult body size ( 32376654 ) Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs) ( 23648065 ) Age-related hearing impairment ( 24939585 ) Atorvastatin-induced myopathy ( 31220337 ) Body mass index ( 25673413 28892062 ) Body size at age 10 ( 32376654 ) Cerebrospinal P-tau181p levels ( 28247064 ) Chin dimples ( 27182965 ) Chronotype ( 30696823 ) Falling risk ( 32999390 ) General risk tolerance (MTAG) ( 30643258 ) High density lipoprotein cholesterol levels ( 34074324 ) Major depressive disorder ( 27479909 ) Myocardial infarction in hypertension (calcium channel blocker interaction) ( 26516778 ) Myopia (pathological) ( 23049088 ) Obesity-related traits ( 23251661 ) Remission after SSRI treatment in major depression ( 30034349 ) Schizophrenia ( 29483656 30285260 28991256 25056061 ) Select biomarker traits ( 17903293 ) Severe malaria ( 29381699 ) Severe malaria (adjusted for sickle cell variant rs334) ( 29381699 ) Waist circumference adjusted for body mass index ( 34021172 ) Waist-to-hip ratio adjusted for body mass index ( 27195708 )
Entrez ID	9745
HPRD ID	15825
Ensembl ID	ENSG00000198597
Uniprot IDs	A0A994J7Z0 K7EQN6 O15090
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Maintenance Of Transcriptional Fidelity During Transcription Elongation By RNA Polymerase II