SEMA3E

Description		semaphorin 3E
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane
	Molecular Function	Protein Binding Semaphorin Receptor Binding Neuropilin Binding Chemorepellent Activity Receptor Ligand Activity
	Biological Process	Angiogenesis Branching Involved In Blood Vessel Morphogenesis Neural Crest Cell Migration Negative Regulation Of Cell-matrix Adhesion Sprouting Angiogenesis Nervous System Development Axon Guidance Regulation Of Cell Shape Negative Regulation Of Angiogenesis Gonadotrophin-releasing Hormone Neuronal Migration To The Hypothalamus Cell Differentiation Positive Regulation Of Cell Migration Forebrain Development Negative Regulation Of Neuron Apoptotic Process Synapse Organization Negative Chemotaxis Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Semaphorin-plexin Signaling Pathway
Pathways		Other semaphorin interactions
Drugs
Diseases		CHARGE syndrome
GWAS		Asthma (childhood onset) ( 27142222) Blood protein levels ( 30072576) Cognitive performance (processing speed) ( 31598132) Epithelial ovarian cancer ( 25134534) Heel bone mineral density ( 28869591 30598549) Lateral ventricle temporal horn volume ( 31530798) Metabolite levels ( 23823483) Nose morphology ( 29921221) Rosacea symptom severity ( 29771307)
Interacting Genes		1 interacting genes: CFTR
Entrez ID		9723
HPRD ID		11545
Ensembl ID		ENSG00000170381
Uniprot IDs		O15041
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of Enamel Mineralization Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Transepithelial Water Transport Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Amelogenesis ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Regulation Of Monoatomic Anion Transport Epithelial Fluid Transport Golgi-associated Vesicle Membrane Cellular Response To Forskolin Response To Forskolin Chloride Transmembrane Transporter Activity Sperm Capacitation Bicarbonate Transport Water Transport Multicellular Organismal-level Water Homeostasis Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Ion Transmembrane Transporter Activity Cholesterol Biosynthetic Process 14-3-3 Protein Binding Fluid Transport Transepithelial Transport Vesicle Docking Involved In Exocytosis Positive Regulation Of Transporter Activity ABC-type Transporter Activity Sterol Biosynthetic Process Chloride Channel Complex Positive Regulation Of Biomineral Tissue Development Cellular Response To CAMP Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Vesicle Docking Cholesterol Transport Clathrin-coated Endocytic Vesicle Membrane Odontogenesis Of Dentin-containing Tooth Chloride Channel Activity Multicellular Organismal-level Chemical Homeostasis Regulation Of Cellular PH Regulation Of Transmembrane Transporter Activity Membrane Docking Positive Regulation Of Exocytosis
Tagcloud ?