TRAM2

Description		translocation associated membrane protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Protein Binding
	Biological Process	SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation Protein Transport Collagen Biosynthetic Process Protein Insertion Into ER Membrane
Pathways
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Appendicular lean mass ( 33097823) Atopic march ( 26542096) Intraocular pressure ( 29617998) LDL cholesterol levels ( 28334899) Lipid traits (pleiotropy) (HIPO component 2) ( 30289880) Low density lipoprotein cholesterol levels ( 29083408) Total cholesterol levels ( 28334899)
Novel Interacting Genes		1 novel interacting genes: PTK7
Interacting Genes		4 interacting genes: GTF2B GTF2F2 POLR2A TBP
Entrez ID		9697
HPRD ID		16338
Ensembl ID		ENSG00000065308
Uniprot IDs		A0A024RD84 Q15035
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Polymerase II General Transcription Initiation Factor Activity Transcription Initiation At RNA Polymerase II Promoter Transcription By RNA Polymerase II DNA-templated Transcription Initiation DNA-templated Transcription RNA Polymerase II Core Promoter Sequence-specific DNA Binding Transcription Factor TFIID Complex Nucleobase-containing Compound Biosynthetic Process Transcription Elongation By RNA Polymerase II MRNA Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly DNA-templated Transcription Elongation MRNA Transcription Transcription Preinitiation Complex Assembly Promoter-specific Chromatin Binding RNA Metabolic Process Macromolecule Biosynthetic Process Transcriptional Start Site Selection At RNA Polymerase II Promoter RNA Polymerase II, Holoenzyme RNA Polymerase II Core Complex Assembly RNA Polymerase II Transcription Regulator Complex Transcription Factor TFIIF Complex Positive Regulation Of Core Promoter Binding Nucleic Acid Metabolic Process RNA-directed RNA Polymerase Activity RNA-templated Transcription DNA Binding DNA-binding Transcription Factor Binding Germinal Vesicle Protein-DNA Complex Assembly TFIIB-class Transcription Factor Binding Microfibril Binding RNA Polymerase Transcription Factor SL1 Complex Transcription Factor TFIIA Complex Viral Transcription 5'-3' RNA Polymerase Activity RNA Polymerase II General Transcription Initiation Factor Binding Pronucleus Nucleobase-containing Compound Metabolic Process Male Pronucleus Aryl Hydrocarbon Receptor Binding Lung-associated Mesenchyme Development RNA Polymerase I Core Promoter Sequence-specific DNA Binding RNA Polymerase I Preinitiation Complex Assembly Female Pronucleus Meiotic Sister Chromatid Cohesion Positive Regulation Of Transcription Regulatory Region DNA Binding Axon Guidance Receptor Activity RNA Polymerase III General Transcription Initiation Factor Activity Transcription Preinitiation Complex
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