LPIN2

Description		lipin 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Membrane
	Molecular Function	Transcription Coactivator Activity Phosphatidate Phosphatase Activity Hydrolase Activity
	Biological Process	Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Catabolic Process Triglyceride Biosynthetic Process Cellular Response To Insulin Stimulus Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Synthesis of PC Synthesis of PE Depolymerization of the Nuclear Lamina Triglyceride biosynthesis
Drugs
Diseases		Majeed syndrome; Chronic recurrent multifocal osteomyelitis (CRMO)
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Apolipoprotein A1 levels ( 32203549) Body mass index in asthmatics ( 23517042) Mean reticulocyte volume ( 32888494) Night sleep phenotypes ( 27126917) Red cell distribution width ( 32888494) Reticulocyte fraction of red cells ( 32888494) Type 2 diabetes ( 21490949) Urinary albumin-to-creatinine ratio in non-diabetics ( 26631737)
Interacting Genes		1 interacting genes: PPP1CA
Entrez ID		9663
HPRD ID		16114
Ensembl ID		ENSG00000101577
Uniprot IDs		Q92539
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Polymerase II Promoter Clearance Regulation Of Glycogen Catabolic Process Positive Regulation Of Termination Of DNA-templated Transcription Glycogen Granule Regulation Of Translational Initiation In Response To Stress Positive Regulation Of Termination Of RNA Polymerase II Transcription PTW/PP1 Phosphatase Complex Double-strand Break Repair Via Alternative Nonhomologous End Joining RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Termination Of RNA Polymerase II Transcription, Poly(A)-coupled Telomere Maintenance In Response To DNA Damage Protein Phosphatase Type 1 Complex Transition Metal Ion Binding Cadherin Binding Involved In Cell-cell Adhesion Positive Regulation Of Glycogen Biosynthetic Process Response To Lead Ion Entrainment Of Circadian Clock By Photoperiod Regulation Of Translation In Response To Stress Negative Regulation Of Transcription Elongation By RNA Polymerase II Protein Phosphatase 1 Binding Negative Regulation Of DNA-templated Transcription, Elongation Photoperiodism Entrainment Of Circadian Clock Regulation Of Glycogen Biosynthetic Process Ribonucleoprotein Complex Binding Positive Regulation Of Protein-containing Complex Disassembly Regulation Of Glycogen Metabolic Process Positive Regulation Of Glucose Metabolic Process Transcription Elongation By RNA Polymerase II Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand DNA-templated Transcription Elongation Glycogen Metabolic Process Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Double-strand Break Repair Via Nonhomologous End Joining Positive Regulation Of Transcription Elongation By RNA Polymerase II Positive Regulation Of DNA-templated Transcription, Elongation Regulation Of Carbohydrate Catabolic Process Circadian Regulation Of Gene Expression Energy Reserve Metabolic Process Polysaccharide Metabolic Process Phosphatase Activity Protein Dephosphorylation Protein Serine/threonine Phosphatase Activity Regulation Of Transcription Elongation By RNA Polymerase II Telomere Maintenance Regulation Of Glucose Metabolic Process Lung Development Regulation Of DNA-templated Transcription Elongation Regulation Of Translational Initiation
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