MTRF1

Description		mitochondrial translation release factor 1
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GO Annotations	Cellular Component	Cytoplasm Mitochondrion
	Molecular Function	Translation Release Factor Activity Translation Release Factor Activity, Codon Specific
	Biological Process	Translation Translational Termination Mitochondrial Translational Termination
Pathways		Mitochondrial translation termination
Drugs
Diseases
GWAS		Keratoconus ( 33649486) Proportion of activated microglia (inferior temporal cortex) ( 30679421)
Novel Interacting Genes		2 novel interacting genes: NUDT15 RB1
Interacting Genes
Entrez ID		9617
HPRD ID		06855
Ensembl ID		ENSG00000120662
Uniprot IDs		O75570
PDB IDs		8OIN 8OIP 8OIQ 8OIR 8OIS 8OIT
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Myofibroblast Differentiation Sister Chromatid Biorientation Maintenance Of Mitotic Sister Chromatid Cohesion Regulation Of Lipid Kinase Activity Negative Regulation Of Hepatocyte Apoptotic Process Enucleate Erythrocyte Differentiation Glial Cell Apoptotic Process Rb-E2F Complex Regulation Of Centromere Complex Assembly Chromatin Lock Complex Positive Regulation Of Collagen Fibril Organization 8-oxo-7,8-dihydroguanosine Triphosphate Pyrophosphatase Activity Purine Deoxyribonucleoside Triphosphate Catabolic Process 8-oxo-dGDP Phosphatase Activity DGTP Metabolic Process DGTP Catabolic Process Nucleoside Triphosphate Diphosphatase Activity 8-oxo-7,8-dihydrodeoxyguanosine Triphosphate Pyrophosphatase Activity DNA Protection Deoxyribonucleoside Triphosphate Catabolic Process Regulation Of Myofibroblast Differentiation Regulation Of Collagen Fibril Organization Cyclin/CDK Positive Transcription Elongation Factor Complex Importin-alpha Family Protein Binding Deoxyribonucleoside Triphosphate Metabolic Process Positive Regulation Of Transcription Regulatory Region DNA Binding Nucleoside Triphosphate Catabolic Process Positive Regulation Of Macrophage Differentiation Hepatocyte Apoptotic Process Negative Regulation Of Glial Cell Proliferation Positive Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Transcription Regulatory Region DNA Binding Positive Regulation Of Mitotic Sister Chromatid Separation Positive Regulation Of DNA Binding Cell Morphogenesis Involved In Neuron Differentiation Disordered Domain Specific Binding Positive Regulation Of Extracellular Matrix Organization Glial Cell Proliferation Negative Regulation Of Epithelial Cell Apoptotic Process Regulation Of Macrophage Differentiation Deoxyribose Phosphate Catabolic Process Deoxyribonucleotide Catabolic Process Xenobiotic Catabolic Process Neuron Maturation SWI/SNF Complex Myoblast Differentiation Positive Regulation Of Chromosome Separation Aortic Valve Morphogenesis Attachment Of Spindle Microtubules To Kinetochore Negative Regulation Of Smoothened Signaling Pathway
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