SPAG6

Description		sperm associated antigen 6
Image		No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Extracellular Region Nucleus Cytoplasm Cytoskeleton Microtubule Cilium Axoneme Microtubule Cytoskeleton Motile Cilium Cell Projection Sperm Principal Piece
	Molecular Function	Microtubule Binding
	Biological Process	Epithelial Cilium Movement Involved In Extracellular Fluid Movement Sperm Axoneme Assembly Cell Projection Organization Filopodium Assembly Neuron Projection Extension
Pathways
Drugs
Diseases
GWAS		Height ( 31562340) Positive urgency ( 30718321) Prostate-specific antigen levels ( 28139693)
Interacting Genes		2 interacting genes: APP SPAG16
Entrez ID		9576
HPRD ID		09305
Ensembl ID		ENSG00000077327
Uniprot IDs		A0A0A0MRT8 A0A140VJU9 O75602
PDB IDs
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Microtubule-based Transport Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Axonemal Central Apparatus Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Microtubule-based Movement Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion Mucociliary Clearance Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding Plasma Membrane Bounded Cell Projection Organization Acetylcholine Receptor Binding Golgi-associated Vesicle Insulin Receptor Binding Apolipoprotein Binding Response To Lead Ion
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