GDF3

Description		growth differentiation factor 3
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm
	Molecular Function	Cytokine Activity Growth Factor Activity Protein Kinase Binding
	Biological Process	Skeletal System Development Eye Development In Utero Embryonic Development Response To Dietary Excess Signal Transduction Endoderm Development Mesoderm Development Regulation Of Cell Fate Commitment BMP Signaling Pathway Negative Regulation Of BMP Signaling Pathway Notochord Development Somite Rostral/caudal Axis Specification Positive Regulation Of Fat Cell Differentiation Negative Regulation Of Epidermal Cell Differentiation Negative Regulation Of Myoblast Differentiation Animal Organ Development Formation Of Anatomical Boundary Primitive Streak Formation Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Pathways
Drugs
Diseases		Anophthalmia and microphthalmia (A/M) Klippel-Feil syndrome(KFS)
GWAS		Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
Interacting Genes		1 interacting genes: CRIPTO
Entrez ID		9573
HPRD ID		05938
Ensembl ID		ENSG00000184344
Uniprot IDs		Q9NR23
PDB IDs
Enriched GO Terms of Interacting Partners?		Activin Receptor Binding Response To Hepatocyte Growth Factor Nodal Signaling Pathway Anterior/posterior Axis Specification, Embryo Cellular Response To Hepatocyte Growth Factor Stimulus Nodal Binding Cellular Response To Interleukin-6 Mammary Gland Development Positive Regulation Of MAP Kinase Activity Blood Vessel Endothelial Cell Migration Anterior/posterior Axis Specification Response To Interleukin-6 Activin Receptor Signaling Pathway Cell Migration Involved In Sprouting Angiogenesis Embryonic Axis Specification Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Cellular Response To Epidermal Growth Factor Stimulus Response To Epidermal Growth Factor Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of MAP Kinase Activity Embryonic Pattern Specification Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cellular Response To Type II Interferon Axis Specification Determination Of Bilateral Symmetry Endothelial Cell Migration Determination Of Left/right Symmetry Response To Type II Interferon Cellular Response To Tumor Necrosis Factor Response To Tumor Necrosis Factor Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Endothelial Cell Migration Side Of Membrane Positive Regulation Of Protein Kinase Activity Positive Regulation Of Kinase Activity Blood Vessel Development Anterior/posterior Pattern Specification Morphogenesis Of A Branching Structure Growth Factor Activity Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Regulation Of Endothelial Cell Migration Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Membrane Raft Regulation Of Protein Kinase Activity Heart Development Embryo Development Ending In Birth Or Egg Hatching Multicellular Organism Development Positive Regulation Of Phosphorylation
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