ADAMTS2

Gene Name		ADAM metallopeptidase with thrombospondin type 1 motif, 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Proteinaceous Extracellular Matrix
	Molecular Function	Metalloendopeptidase Activity Metallopeptidase Activity Zinc Ion Binding
	Biological Process	Proteolysis Spermatogenesis Protein Processing Extracellular Matrix Organization Collagen Fibril Organization Lung Development Collagen Catabolic Process Skin Development
Pathways		Collagen formation Post-translational protein modification Collagen biosynthesis and modifying enzymes O-glycosylation of TSR domain-containing proteins O-linked glycosylation
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder (time to onset) ( 18937294) Stroke (pediatric) ( 22990015) Visceral adipose tissue adjusted for BMI ( 22589738)
Protein-protein Interactions		1 interactors: PIK3R1
Entrez ID		9509
HPRD ID		05173
Ensembl ID		ENSG00000087116
Uniprot IDs		O95450
PDB IDs
Enriched GO Terms of Interacting Partners?		NFAT Protein Import Into Nucleus Transcription Factor Import Into Nucleus Positive Regulation Of Endoplasmic Reticulum Unfolded Protein Response Insulin-like Growth Factor Receptor Signaling Pathway Phosphatidylinositol 3-kinase Signaling Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Growth Hormone Receptor Signaling Pathway Positive Regulation Of Protein Localization To Plasma Membrane Cellular Response To Growth Hormone Stimulus Negative Regulation Of Osteoclast Differentiation Positive Regulation Of RNA Splicing Negative Regulation Of Cell-matrix Adhesion Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Transcription Factor Import Into Nucleus Response To Growth Hormone Regulation Of Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Glucose Import Regulation Of Phosphatidylinositol 3-kinase Activity Negative Regulation Of Myeloid Leukocyte Differentiation Positive Regulation Of Glucose Transport Negative Regulation Of Cell-substrate Adhesion Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Tumor Necrosis Factor Production Regulation Of Lipid Kinase Activity Cellular Response To UV Regulation Of Glucose Import Regulation Of Osteoclast Differentiation Cellular Glucose Homeostasis T Cell Costimulation Negative Regulation Of Myeloid Cell Differentiation Phosphatidylinositol Phosphorylation Regulation Of Transcription Factor Import Into Nucleus Lipid Phosphorylation Cellular Response To Light Stimulus Protein Stabilization Regulation Of Tumor Necrosis Factor Production Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Protein Import Into Nucleus Regulation Of Glucose Transport Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of RNA Splicing B Cell Differentiation Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Localization To Nucleus T Cell Receptor Signaling Pathway Regulation Of Myeloid Leukocyte Differentiation Regulation Of Cell-matrix Adhesion Protein Import Into Nucleus Phosphatidylinositol Biosynthetic Process
Tagcloud ?		aldh1a3 alpl2 apod cabin1 casp10 cdh16 classes classifier clgn covering crabp1 dataset datasets enrichments follicular gnas hmgb2 krthb5 microfollicular nr2f2 nras pax8 predictions sdha separating similarities subclasses timp1 usp13