CDYL

Description		chromodomain Y like
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GO Annotations	Cellular Component	Nucleus Chromosome Cytoplasm Nuclear Speck
	Molecular Function	Chromatin Binding Transcription Corepressor Activity Protein Binding Lyase Activity Protein-macromolecule Adaptor Activity Identical Protein Binding Crotonyl-CoA Hydratase Activity
	Biological Process	Spermatogenesis Spermatid Development Cell Differentiation Negative Regulation Of DNA-templated Transcription Random Inactivation Of X Chromosome Negative Regulation Of Peptidyl-lysine Crotonylation
Pathways
Drugs
Diseases
GWAS		Age at smoking initiation in chronic obstructive pulmonary disease ( 21685187) Body mass index ( 28552196) Cellular nuclear factor (erythroid-derived 2)-like 2 levels ( 30767168) Red cell distribution width ( 32888494) Response to ketogenic dietary therapies in epilepsy ( 30009487) Weight ( 28552196)
Interacting Genes		9 interacting genes: FXR1 H3-4 H3C1 HDAC1 HDAC2 HTRA1 LIG1 REST TTC9C
Entrez ID		9425
HPRD ID		04803
Ensembl ID		ENSG00000153046
Uniprot IDs		Q9Y232
PDB IDs		2DNT 2GTR 7N27
Enriched GO Terms of Interacting Partners?		Protein Decrotonylase Activity Histone Decrotonylase Activity Protein Lysine Delactylase Activity Fungiform Papilla Formation Positive Regulation Of Stem Cell Population Maintenance Hair Follicle Placode Formation Regulation Of Stem Cell Population Maintenance Regulation Of Stem Cell Differentiation Chromatin Remodeling Histone Deacetylase Activity, Hydrolytic Mechanism Host-mediated Suppression Of Viral Transcription Eyelid Development In Camera-type Eye Protein Lysine Deacetylase Activity Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Neurogenesis Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Linear Amides Host-mediated Suppression Of Viral Proces NuRD Complex Chromatin Organization Histone Deacetylase Activity Regulation Of Nervous System Development RNA Polymerase II Core Promoter Sequence-specific DNA Binding Positive Regulation Of Oligodendrocyte Differentiation Sin3-type Complex Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cell Fate Specification Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Stem Cell Population Maintenance Host-mediated Perturbation Of Viral Transcription RNA Polymerase II-specific DNA-binding Transcription Factor Binding NF-kappaB Binding Regulation Of Intracellular Estrogen Receptor Signaling Pathway Positive Regulation Of Neurogenesis Nucleosomal DNA Binding Positive Regulation Of Glial Cell Differentiation Regulation Of Oligodendrocyte Differentiation Histone Deacetylase Complex Regulation Of Cell Fate Commitment Positive Regulation Of Nervous System Development Heterochromatin Epigenetic Regulation Of Gene Expression Embryonic Digit Morphogenesis Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Gliogenesis Transcription Repressor Complex Positive Regulation Of Male Mating Behavior Okazaki Fragment Processing Involved In Mitotic DNA Replication Negative Regulation Of Dense Core Granule Biogenesis Negative Regulation Of Amniotic Stem Cell Differentiation
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